Preferred Name |
Warfarin |
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Synonyms |
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|
ID |
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571352688529240169 |
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altLabel |
苄酮香豆素钠 华法林 Panwarfin 苄丙酮香豆素 华法林 Sofarin Coumadin 华法灵 丙酮苄羟香豆素 |
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definition |
Warfarin, a coumarin derivative, produces an anticoagulant effect by interfering with the cyclic interconversion of vitamin K and its 2,3 epoxide (vitamin K epoxide). Vitamin K is a cofactor for the carboxylation of glutamate residues to γ-carboxyglutamates (Gla) on the N-terminal regions of vitamin K–dependent proteins . |
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label |
Warfarin 华法林 |
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oboInOwl:hasDbXref | ||
prefLabel |
Warfarin |
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references |
Hirsh, J., Fuster, V., Ansell, J., & Halperin, J. L. (2003). American Heart Association/American College of Cardiology Foundation guide to warfarin therapy1. Journal of the American College of Cardiology, 41(9), 1633-1652. |
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subClassOf |
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571352688529240144 |