loading...| Preferred Name | ciliary marginal zone | |
| Synonyms |
circumferential germinal zone retinal proliferative zone CMZ peripheral growth zone retinal ciliary marginal zone |
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| Definitions |
Region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth.[Wehman et al, 2005]. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0003065 |
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| database_cross_reference |
VHOG:0000088 EFO:0003668 ZFA:0001289 XAO:0000086 TAO:0001289 AAO:0010342 |
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| definition |
Region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth.[Wehman et al, 2005]. |
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| external_definition |
Region at the periphery of the retina where retinal stem cells are located. After 60 hpf, the CMZ is the source of most retinal growth. Wehman et al, 2005.[TAO] |
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| has part | ||
| has_exact_synonym |
peripheral growth zone retinal ciliary marginal zone |
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| has_obo_namespace |
uberon |
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| has_related_synonym |
circumferential germinal zone retinal proliferative zone CMZ |
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| homology_notes |
The retina of all vertebrates develops via similar mechanisms. Toward the end of retinal histogenesis, proliferating progenitors and newly generated cells are confined to peripheral regions of the retina. In fish and amphibians, this region is maintained after embryonic development and becomes the CMZ (ciliary margin zone). A CMZ exists in birds but compared to that of fish and amphibians this region produces much less new retina as the globe of the eye expands postnatally. At least some of the molecular mechanisms that regulate the addition of new cells in this zone appear to have been conserved from fish to birds.[well established][VHOG] |
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| id |
UBERON:0003065 |
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| in_subset | ||
| label |
ciliary marginal zone |
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| notation |
UBERON:0003065 |
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| overlaps | ||
| part_of | ||
| prefLabel |
ciliary marginal zone |
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| treeView | ||
| subClassOf |