Preferred Name |
insulin |
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Synonyms |
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Definitions |
A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_145810 |
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database_cross_reference |
PMID:19251032 Wikipedia:Insulin PMID:6069707 PMID:5941964 PMID:12137720 PMID:25848166 |
|
definition |
A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies. |
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has_obo_namespace |
chebi_ontology |
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id |
CHEBI:145810 |
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in_subset | ||
label |
insulin |
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notation |
CHEBI:145810 |
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prefLabel |
insulin |
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subClassOf |
http://purl.obolibrary.org/obo/CHEBI_24533 |