Link to this page
Toxic Process Ontology
| Preferred Name | busulfan | |
| Synonyms |
busulfan Mablin busulfanum Mitostan busulfano Tetramethylene bis(methanesulfonate) Leucosulfan Misulban 1,4-Bis(methanesulfonoxy)butane Myleran 1,4-Dimethanesulfonoxybutane 1,4-Dimesyloxybutane Mielucin 1,4-Butanediol dimethanesulfonate Bisulfex Myeloleukon butane-1,4-diyl dimethanesulfonate Busulfan |
|
| Definitions |
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_28901 |
|
| database_cross_reference |
DrugBank:DB01008 PMID:19361744 CAS:55-98-1 PMID:19611402 PMID:10523796 Drug_Central:438 LINCS:LSM-5388 Reaxys:1791786 Beilstein:1791786
|
|
| definition |
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.
|
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_50905 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_67105 |
|
| has_exact_synonym |
butane-1,4-diyl dimethanesulfonate Busulfan
|
|
| has_related_synonym |
busulfan Mablin busulfanum Mitostan busulfano Tetramethylene bis(methanesulfonate) Leucosulfan Misulban 1,4-Bis(methanesulfonoxy)butane Myleran 1,4-Dimethanesulfonoxybutane 1,4-Dimesyloxybutane Mielucin 1,4-Butanediol dimethanesulfonate Bisulfex Myeloleukon
|
|
| id |
CHEBI:28901
|
|
| label |
busulfan
|
|
| notation |
CHEBI:28901
|
|
| prefLabel |
busulfan
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |