loading...| Preferred Name |
Pulmonary Hypertension |
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| Synonyms |
Increased Blood Pressure in Blood Vessels of Lungs Pulmonary Arterial Hypertension |
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| Definitions |
Pulmonary hypertension can be secondary to known cardiac, pulmonary, or hepatic disease. If no cause is identifiable, the term primary pulmonary hypertension is used. An elevation of mean pulmonary arterial systolic pressure (mPASP) (>20 mmHg at rest or >30 mmHg with exercise). The 6th World Symposium on PH reduced it from >25mmHg to >20mmHg for at rest, but did not adjust the definition for PH with exercise. |
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| ID |
http://purl.obolibrary.org/obo/SCDO_0000943 |
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| rdfs:comment |
Pulmonary hypertension can be secondary to known cardiac, pulmonary, or hepatic disease. If no cause is identifiable, the term primary pulmonary hypertension is used. |
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| dc:source | ||
| definition |
An elevation of mean pulmonary arterial systolic pressure (mPASP) (>20 mmHg at rest or >30 mmHg with exercise). The 6th World Symposium on PH reduced it from >25mmHg to >20mmHg for at rest, but did not adjust the definition for PH with exercise. |
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| definition source |
Simonneau et al 2013 J Am Coll Cardiol; Ataga et al. Br J Haematol. 2006 Jul;134(1):109-15. |
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| diagnosed using tool |
http://purl.obolibrary.org/obo/NCIT_C18772 |
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| existence in other ontologies |
Few but definitions not specific enough |
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| hasExactSynonym |
Increased Blood Pressure in Blood Vessels of Lungs Pulmonary Arterial Hypertension |
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| in guideline |
http://purl.obolibrary.org/obo/SCDO_1000150 http://purl.obolibrary.org/obo/SCDO_1000151 http://purl.obolibrary.org/obo/SCDO_1000154 http://purl.obolibrary.org/obo/SCDO_1000153 http://purl.obolibrary.org/obo/SCDO_1000152 http://purl.obolibrary.org/obo/SCDO_1000144 http://purl.obolibrary.org/obo/SCDO_1000149 http://purl.obolibrary.org/obo/SCDO_1000148 |
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| is caused by |
Multifactorial, including chronic thromboembolism, splenectomy, high cardiac output, left-heart disease, and hyperviscosity; the role of an inactivation of nitric oxide by free plasma hemoglobin due to chronic hemolysis is controversial. |
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| prefixIRI |
SCDO:0000943 |
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| prefLabel |
Pulmonary Hypertension |
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| rdfs:label |
Pulmonary Hypertension |
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| subClassOf |