loading...| Preferred Name |
Biomarker |
|
| Synonyms |
Signature Molecule biological marker signature molecule Molecular Marker molecular marker Biological Markers Biological Marker Biomarker Biomarkers Marker biomarker marker |
|
| Definitions |
A characteristic that can be objectively measured and serves as an indicator for normal biologic processes, pathogenic processes, state of health or disease, the risk for disease development and/or prognosis, or responsiveness to a particular therapeutic intervention. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C16342 |
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| ALT_DEFINITION |
A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. A defined characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Molecular, histologic, radiographic, or physiologic characteristics are types of biomarkers. A biomarker is not an assessment of how an individual feels, functions, or survives. Categories of biomarkers include: susceptibility/risk biomarker; diagnostic biomarker; monitoring biomarker; prognostic biomarker; predictive biomarker; safety biomarker; pharmacodynamic/response biomarker. [NIH-FDA BEST (Biomarkers, Endpoints, and other Tools) Resource, https://www.ncbi.nlm.nih.gov/books/NBK338448/] A characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. (From: FDA Guidance for Industry: Pharmacogenomic Data Submissions.) |
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| CHEBI_ID |
CHEBI:59163 |
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| code |
C16342 |
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| Contributing_Source |
CDISC-GLOSS |
|
| definition |
A characteristic that can be objectively measured and serves as an indicator for normal biologic processes, pathogenic processes, state of health or disease, the risk for disease development and/or prognosis, or responsiveness to a particular therapeutic intervention. |
|
| has exact synonym |
Signature Molecule biological marker signature molecule Molecular Marker molecular marker Biological Markers Biological Marker Biomarker Biomarkers Marker biomarker marker |
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| imported from | ||
| in subset | ||
| label |
Biomarker |
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| Legacy_Concept_Name |
Biomarker |
|
| Preferred_Name |
Biomarker |
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| prefixIRI |
NCIT:C16342 |
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| prefLabel |
Biomarker |
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| Semantic_Type |
Functional Concept |
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| UMLS_CUI |
C0005516 |
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| subClassOf |