PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Smooth Muscle Contraction
Synonyms
Definitions

"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732]

ID

http://www.phoc.org.cn/pmo/class/PMO_00068776

Database_Cross_Reference

GO:0006939

Definition

"A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732]

Gene Annotation

NMUR1(UniProtKB:Q9HB89)

EDNRA(UniProtKB:P25101)

ADRA1A(UniProtKB:P35348)

BDKRB2(UniProtKB:P30411)

CHRNB2(UniProtKB:P17787)

MLN(UniProtKB:P12872)

PDE4D(UniProtKB:Q08499)

FKBP1B(UniProtKB:P68106)

HTR7(UniProtKB:P34969)

MYLK(UniProtKB:Q15746)

CHRNB4(UniProtKB:P30926)

ROCK2(UniProtKB:O75116)

SMTN(UniProtKB:P53814)

MYH11(UniProtKB:P35749)

CHRM3(UniProtKB:P20309)

TPCN2(UniProtKB:Q8NHX9)

ROCK1(UniProtKB:Q13464)

label

Smooth Muscle Contraction

MCID

MC04765305

PMOID

PMO:00068776

prefixIRI

pmo:PMO_00068776

prefLabel

Smooth Muscle Contraction

Synonym

"visceral muscle contraction" EXACT []

Tree Number

T10.1.25.19.5.3.1

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00068775

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/GO_0006939 UBERON LOOM
http://purl.obolibrary.org/obo/GO_0006939 CL LOOM
http://purl.obolibrary.org/obo/GO_0006939 OBA LOOM
http://purl.obolibrary.org/obo/HINO_0016385 HINO LOOM
http://purl.jp/bio/4/id/200906065751307838 IOBC LOOM
http://scai.fraunhofer.de/PWDICT#ID1693 PTS LOOM
http://purl.obolibrary.org/obo/GO_0006939 GO-EXT LOOM
http://purl.obolibrary.org/obo/GO_0006939 UBERON LOOM
http://purl.obolibrary.org/obo/GO_0006939 INBANCIDO LOOM
http://purl.obolibrary.org/obo/GO_0006939 CCONT LOOM
http://purl.obolibrary.org/obo/GO_0006939 FOVT LOOM
http://purl.obolibrary.org/obo/GO_0006939 HOIP LOOM
http://purl.obolibrary.org/obo/GO_0006939 RBO LOOM
http://purl.obolibrary.org/obo/GO_0006939 EFO LOOM
http://purl.obolibrary.org/obo/GO_0006939 XPO LOOM
http://purl.obolibrary.org/obo/GO_0006939 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0006939 PCL LOOM
http://purl.obolibrary.org/obo/GO_0006939 PATO LOOM
http://purl.obolibrary.org/obo/GO_0006939 NIFDYS LOOM
http://purl.obolibrary.org/obo/GO_0006939 GO-PLUS LOOM
http://purl.obolibrary.org/obo/GO_0006939 BERO LOOM
http://purl.obolibrary.org/obo/GO_0006939 NBO LOOM
http://purl.obolibrary.org/obo/GO_0006939 HHEAR LOOM
http://purl.obolibrary.org/obo/GO_0006939 GSSO LOOM
http://purl.obolibrary.org/obo/GO_0006939 CIDO LOOM
http://purl.obolibrary.org/obo/GO_0006939 UPHENO LOOM
http://purl.obolibrary.org/obo/GO_0006939 FTC LOOM
http://purl.obolibrary.org/obo/GO_0006939 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0006939 ECAO LOOM
http://purl.obolibrary.org/obo/GO_0006939 REGN_GO LOOM
http://purl.obolibrary.org/obo/GO_0006939 GO LOOM
http://purl.obolibrary.org/obo/GO_0006939 ZP LOOM
http://purl.obolibrary.org/obo/GO_0006939 AISM LOOM
http://purl.obolibrary.org/obo/GO_0006939 NMDCO LOOM
http://purl.obolibrary.org/obo/GO_0006939 OBA LOOM
http://purl.org/obo/owl/GO#GO_0006939 BIOMODELS LOOM