Link to this page
PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
Jump to:
| Preferred Name | Cytoskeleton | |
| Synonyms |
|
|
| Definitions |
"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, ISBN:0198547684, PMID:16959967] |
|
| ID |
http://www.phoc.org.cn/pmo/class/PMO_00054039 |
|
| Database_Cross_Reference |
GO:0005856
|
|
| Definition |
"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, ISBN:0198547684, PMID:16959967]
|
|
| Gene Annotation |
DEF6(UniProtKB:Q9H4E7) PDE6D(UniProtKB:O43924) SDCBP(UniProtKB:O00560) TBC1D21(UniProtKB:Q8IYX1) CFAP298(UniProtKB:P57076) MAP2K6(UniProtKB:P52564) HINT1(UniProtKB:P49773) CIT(UniProtKB:O14578) CDC42BPA(UniProtKB:Q5VT25) WDR19(UniProtKB:Q8NEZ3) ARHGAP39(UniProtKB:Q9C0H5) KIF1BP(UniProtKB:Q96EK5) TYK2(UniProtKB:P29597) PICK1(UniProtKB:Q9NRD5) UBXN11(UniProtKB:Q5T124) CALD1(UniProtKB:Q05682) KLHL5(UniProtKB:Q96PQ7) PLEKHH3(UniProtKB:Q7Z736) ARHGEF2(UniProtKB:Q92974) IGF2BP2(UniProtKB:Q9Y6M1) SNTG2(UniProtKB:Q9NY99) FCHO2(UniProtKB:Q0JRZ9) FNBP1L(UniProtKB:Q5T0N5) PLEKHH1(UniProtKB:Q9ULM0) ABI2(UniProtKB:Q9NYB9) FRMD4B(UniProtKB:Q9Y2L6) NOD2(UniProtKB:Q9HC29) CTNNAL1(UniProtKB:Q9UBT7) MACF1(UniProtKB:Q9UPN3) A0A3B3ITR4(UniProtKB:A0A3B3ITR4) TEC(UniProtKB:P42680) PDLIM4(UniProtKB:P50479) FGR(UniProtKB:P09769) PACSIN1(UniProtKB:Q9BY11) FGD2(UniProtKB:Q7Z6J4) ALDOC(UniProtKB:P09972) DRC7(UniProtKB:Q8IY82) DBN1(UniProtKB:Q16643) CAPZB(UniProtKB:P47756) TNS4(UniProtKB:Q8IZW8) TMEM216(UniProtKB:Q9P0N5) HTRA2(UniProtKB:O43464) PFN3(UniProtKB:P60673) CDK5RAP2(UniProtKB:Q96SN8) TBCEL(UniProtKB:Q5QJ74) MPP2(UniProtKB:Q14168) TPM3(UniProtKB:P06753) ARHGDIA(UniProtKB:P52565) PARD3(UniProtKB:Q8TEW0) MYO1E(UniProtKB:Q12965) MAEA(UniProtKB:Q7L5Y9) AKAP12(UniProtKB:Q02952) FGD4(UniProtKB:Q96M96) JAK1(UniProtKB:P23458) SLC30A9(UniProtKB:Q6PML9) ADD1(UniProtKB:P35611) PARVG(UniProtKB:Q9HBI0) DNAI1(UniProtKB:Q9UI46) S100A12(UniProtKB:P80511) FRMD4A(UniProtKB:Q9P2Q2) TRADD(UniProtKB:Q15628) ENC1(UniProtKB:O14682) ADD3(UniProtKB:Q9UEY8) TNKS1BP1(UniProtKB:Q9C0C2) HIP1(UniProtKB:O00291) RIN1(UniProtKB:Q13671) CALCOCO2(UniProtKB:Q13137) RAC3(UniProtKB:P60763) PTPN13(UniProtKB:Q12923) ANKRA2(UniProtKB:Q9H9E1) BIN1(UniProtKB:O00499) FRMD8P1(UniProtKB:Q9BZ68) TCHH(UniProtKB:Q07283) SSH1(UniProtKB:Q8WYL5) SHROOM2(UniProtKB:Q13796) FRMD1(UniProtKB:Q8N878) CLU(UniProtKB:P10909) FCHO1(UniProtKB:O14526) SGCZ(UniProtKB:Q96LD1) CDC42SE1(UniProtKB:Q9NRR8) TMSB4Y(UniProtKB:O14604) ERC2(UniProtKB:O15083) SHROOM3(UniProtKB:Q8TF72) MCF2(UniProtKB:P10911) TMSB10(UniProtKB:P63313) MYLIP(UniProtKB:Q8WY64) CCT3(UniProtKB:P49368) EVC2(UniProtKB:Q86UK5) SNTG1(UniProtKB:Q9NSN8) JAK2(UniProtKB:O60674) TTC21B(UniProtKB:Q7Z4L5) EPB41L1(UniProtKB:Q9H4G0) CASP8(UniProtKB:Q14790) HSBP1(UniProtKB:O75506) FGD5(UniProtKB:Q6ZNL6) EPB41L5(UniProtKB:Q9HCM4) BRK1(UniProtKB:Q8WUW1) NEK8(UniProtKB:Q86SG6) BASP1(UniProtKB:P80723) PTPN4(UniProtKB:P29074) EPB42(UniProtKB:P16452) TOR1A(UniProtKB:O14656) GYS2(UniProtKB:P54840) RIPOR2(UniProtKB:Q9Y4F9) MARVELD1(UniProtKB:Q9BSK0) PPP2R2B(UniProtKB:Q00005) FRMPD2(UniProtKB:Q68DX3) NPHP1(UniProtKB:O15259) TENM1(UniProtKB:Q9UKZ4) PPP1R12C(UniProtKB:Q9BZL4) LDB3(UniProtKB:O75112) GPHN(UniProtKB:Q9NQX3) PKP4(UniProtKB:Q99569) KRT77(UniProtKB:Q7Z794) GAN(UniProtKB:Q9H2C0) TGFB1I1(UniProtKB:O43294) FSCN3(UniProtKB:Q9NQT6) WASF3(UniProtKB:Q9UPY6) PACSIN2(UniProtKB:Q9UNF0) STXBP1(UniProtKB:P61764) FRMPD4(UniProtKB:Q14CM0) TUBB4B(UniProtKB:P68371) RAI14(UniProtKB:Q9P0K7) NOS3(UniProtKB:P29474) CFAP300(UniProtKB:Q9BRQ4) PPP1R12B(UniProtKB:O60237) EPB41L4B(UniProtKB:Q9H329) SSH2(UniProtKB:Q76I76) RHOBTB2(UniProtKB:Q9BYZ6) ADD2(UniProtKB:P35612) S100A9(UniProtKB:P06702) DCX(UniProtKB:O43602) FNBP1(UniProtKB:Q96RU3) ACTL7A(UniProtKB:Q9Y615) CABP1(UniProtKB:Q9NZU7) VCL(UniProtKB:P18206) GAS2L2(UniProtKB:Q8NHY3) SNTA1(UniProtKB:Q13424) ARL6IP5(UniProtKB:O75915) SYN1(UniProtKB:P17600) SGCG(UniProtKB:Q13326) FRMD7(UniProtKB:Q6ZUT3) PREPL(UniProtKB:Q4J6C6) SLC7A11(UniProtKB:Q9UPY5) FRMD6(UniProtKB:Q96NE9) SPIRE2(UniProtKB:Q8WWL2) SORBS3(UniProtKB:O60504) RNF128(UniProtKB:Q8TEB7) ACTR6(UniProtKB:Q9GZN1) CASS4(UniProtKB:Q9NQ75) KRIT1(UniProtKB:O00522) LRRC10(UniProtKB:Q5BKY1) MAPK3(UniProtKB:P27361) SSH3(UniProtKB:Q8TE77) TMSB15A(UniProtKB:P0CG34) ACTN2(UniProtKB:P35609) MPZL2(UniProtKB:O60487) TRIM67(UniProtKB:Q6ZTA4) RHOA(UniProtKB:P61586) PRKCE(UniProtKB:Q02156) MARCKSL1(UniProtKB:P49006) SAXO1(UniProtKB:Q8IYX7) FARP2(UniProtKB:O94887) JAK3(UniProtKB:P52333) UACA(UniProtKB:Q9BZF9) NME9(UniProtKB:Q86XW9) SGCE(UniProtKB:O43556) TUBB(UniProtKB:P07437) ARHGEF18(UniProtKB:Q6ZSZ5) ARHGAP24(UniProtKB:Q8N264) SYMPK(UniProtKB:Q92797) JUP(UniProtKB:P14923) FARP1(UniProtKB:Q9Y4F1) JMY(UniProtKB:Q8N9B5) TBCC(UniProtKB:Q15814) GAS2L1(UniProtKB:Q99501) STK39(UniProtKB:Q9UEW8) PFN1(UniProtKB:P07737) MFHAS1(UniProtKB:Q9Y4C4) KITLG(UniProtKB:P21583) IVNS1ABP(UniProtKB:Q9Y6Y0) PFN4(UniProtKB:Q8NHR9) CDC42EP5(UniProtKB:Q6NZY7) MSN(UniProtKB:P26038) KLHL1(UniProtKB:Q9NR64) DDX20(UniProtKB:Q9UHI6) MARK1(UniProtKB:Q9P0L2) ITGB1BP1(UniProtKB:O14713) WIPI1(UniProtKB:Q5MNZ9) CNN2(UniProtKB:Q99439) EPB41L3(UniProtKB:Q9Y2J2) DAG1(UniProtKB:Q14118) FBXL13(UniProtKB:Q8NEE6) ANK2(UniProtKB:Q01484) SAXO2(UniProtKB:Q658L1) KLHL41(UniProtKB:O60662) TCTE1(UniProtKB:Q5JU00) FGD1(UniProtKB:P98174) MTCL1(UniProtKB:Q9Y4B5) ROCK2(UniProtKB:O75116) IQCA1(UniProtKB:Q86XH1) INPPL1(UniProtKB:O15357) PTPN21(UniProtKB:Q16825) ARAP3(UniProtKB:Q8WWN8) VIM(UniProtKB:P08670) CDC42BPB(UniProtKB:Q9Y5S2) PSTPIP1(UniProtKB:O43586) SLAIN1(UniProtKB:Q8ND83) FGD3(UniProtKB:Q5JSP0) RAB29(UniProtKB:O14966) CTNNA3(UniProtKB:Q9UI47) CKAP4(UniProtKB:Q07065) KY(UniProtKB:Q8NBH2) EPPK1(UniProtKB:P58107) FRMD3(UniProtKB:A2A2Y4) USH1C(UniProtKB:Q9Y6N9) UXT(UniProtKB:Q9UBK9) RHOF(UniProtKB:Q9HBH0) AKAP4(UniProtKB:Q5JQC9) BICD1(UniProtKB:Q96G01) EVL(UniProtKB:Q9UI08) PCLO(UniProtKB:Q9Y6V0) FLNC(UniProtKB:Q14315) INPP5D(UniProtKB:Q92835) STOML2(UniProtKB:Q9UJZ1) TPM4(UniProtKB:P67936) DMD(UniProtKB:P11532) ACTL9(UniProtKB:Q8TC94) RAB3IP(UniProtKB:Q96QF0) TRIM36(UniProtKB:Q9NQ86) PTPN14(UniProtKB:Q15678) PLEK2(UniProtKB:Q9NYT0) SIPA1L1(UniProtKB:O43166) RAPH1(UniProtKB:Q70E73) TRAF4(UniProtKB:Q9BUZ4) NEXN(UniProtKB:Q0ZGT2) FRMPD1(UniProtKB:Q5SYB0) SGIP1(UniProtKB:Q9BQI5) SPRY2(UniProtKB:O43597) HSPB1(UniProtKB:P04792) CABYR(UniProtKB:O75952) AKAP9(UniProtKB:Q99996) PACSIN3(UniProtKB:Q9UKS6) GAS7(UniProtKB:O60861) ELMOD3(UniProtKB:Q96FG2) PPL(UniProtKB:O60437) FRMPD3(UniProtKB:Q5JV73) COTL1(UniProtKB:Q14019) SNTB1(UniProtKB:Q13884) SPIRE1(UniProtKB:Q08AE8) SH3KBP1(UniProtKB:Q96B97) CMAHP(UniProtKB:Q9Y471) FSCN1(UniProtKB:Q16658) KLHL3(UniProtKB:Q9UH77) SPAG4(UniProtKB:Q9NPE6) CC2D2A(UniProtKB:Q9P2K1) NF2(UniProtKB:P35240) ERMN(UniProtKB:Q8TAM6) PTPN3(UniProtKB:P26045) ARHGDIB(UniProtKB:P52566) PLEKHN1(UniProtKB:Q494U1) PTK2B(UniProtKB:Q14289) LZTS3(UniProtKB:O60299) TRIM46(UniProtKB:Q7Z4K8) PTK2(UniProtKB:Q05397) SYNJ2(UniProtKB:O15056) STOM(UniProtKB:P27105) SMTN(UniProtKB:P53814) KCNC3(UniProtKB:Q14003) FGD6(UniProtKB:Q6ZV73) PINK1(UniProtKB:Q9BXM7) TRIB2(UniProtKB:Q92519) FRMD5(UniProtKB:Q7Z6J6) NR1I3(UniProtKB:Q14994) PTPN7(UniProtKB:P35236) CCDC6(UniProtKB:Q16204) TRIP10(UniProtKB:Q15642) LLGL1(UniProtKB:Q15334) RSPH3(UniProtKB:Q86UC2) CTTN(UniProtKB:Q14247) CLNS1A(UniProtKB:P54105) NEFH(UniProtKB:P12036) DNAJC7(UniProtKB:Q99615) PNP(UniProtKB:P00491) FAM183BP(UniProtKB:Q6ZVS7) FAAH(UniProtKB:O00519) FRMD8(UniProtKB:Q9BZ67) CNN1(UniProtKB:P51911) MYL2(UniProtKB:P10916) SGCB(UniProtKB:Q16585) FERMT1(UniProtKB:Q9BQL6) PFN2(UniProtKB:P35080) DNMBP(UniProtKB:Q6XZF7) ZC3H12A(UniProtKB:Q5D1E8) ARHGAP26(UniProtKB:Q9UNA1) ACTG1(UniProtKB:P63261) MVP(UniProtKB:Q14764) PPP1R18(UniProtKB:Q6NYC8) DHCR24(UniProtKB:Q15392) SNAP25(UniProtKB:P60880) ANK1(UniProtKB:P16157) RIPK2(UniProtKB:O43353) APBB1IP(UniProtKB:Q7Z5R6) TCTN1(UniProtKB:Q2MV58) ABI1(UniProtKB:Q8IZP0) S100A8(UniProtKB:P05109) CAPZA1(UniProtKB:P52907) TRIM9(UniProtKB:Q9C026) SYNE1(UniProtKB:Q8NF91) MAST1(UniProtKB:Q9Y2H9) UTRN(UniProtKB:P46939) CDC42EP1(UniProtKB:Q00587) LRPPRC(UniProtKB:P42704) CSRP3(UniProtKB:P50461) ENAH(UniProtKB:Q8N8S7) EFCAB2(UniProtKB:Q5VUJ9) ALOX15B(UniProtKB:O15296) TPM1(UniProtKB:P09493) EPB41L4A(UniProtKB:Q9HCS5) TMSB15B(UniProtKB:P0CG35) CYS1(UniProtKB:Q717R9) DYRK1A(UniProtKB:Q13627) TNIK(UniProtKB:Q9UKE5) DIXDC1(UniProtKB:Q155Q3) LRRFIP1(UniProtKB:Q32MZ4) WASF1(UniProtKB:Q92558) KAZN(UniProtKB:Q674X7) TRIP11(UniProtKB:Q15643) NOSTRIN(UniProtKB:Q8IVI9) DNAJC24(UniProtKB:Q6P3W2) ROCK1(UniProtKB:Q13464) CDC42BPG(UniProtKB:Q6DT37) KRT16(UniProtKB:P08779) TUBA4A(UniProtKB:P68366) TCTN2(UniProtKB:Q96GX1) TMSB4X(UniProtKB:P62328) TTC25(UniProtKB:Q96NG3) NOS1(UniProtKB:P29475) HAP1(UniProtKB:P54257) SGCA(UniProtKB:Q16586) KIAA0556(UniProtKB:O60303) CEP295(UniProtKB:Q9C0D2) DOCK2(UniProtKB:Q92608) IQCD(UniProtKB:Q96DY2) KRT1(UniProtKB:P04264) SGCD(UniProtKB:Q92629) CDC42SE2(UniProtKB:Q9NRR3) RHOBTB1(UniProtKB:O94844) ACTB(UniProtKB:P60709) MAPK1(UniProtKB:P28482) TNS1(UniProtKB:Q9HBL0) SWAP70(UniProtKB:Q9UH65) OSBPL10(UniProtKB:Q9BXB5) EDA(UniProtKB:Q92838) TLN1(UniProtKB:Q9Y490) FUZ(UniProtKB:Q9BT04) DGKQ(UniProtKB:P52824) PSTPIP2(UniProtKB:Q9H939) LRRC26(UniProtKB:Q2I0M4)
|
|
| label |
Cytoskeleton
|
|
| MCID |
MC04764115
|
|
| PMOID |
PMO:00054039
|
|
| prefixIRI |
pmo:PMO_00054039
|
|
| prefLabel |
Cytoskeleton
|
|
| Tree Number |
T10.3.4.7.4.24 T10.3.4.4.3.24 T10.3.7.100.15.3.24
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping