Preferred Name | Vitamin_K | |
Synonyms |
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ID |
http://www.owl-ontologies.com/Ontology1358660052.owl#Vitamin_K |
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ID |
C943 |
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NCI_Definition |
The term "vitamin K" refers to a group of chemically similar fat-soluble compounds called naphthoquinones: vitamin K1 (phytonadione) is found in plants and is the primary source of vitamin K for humans through dietary consumption, vitamin K2 compounds (menaquinones) are made by bacteria in the human gut, and vitamin K3 (menadione) is a water-soluble preparation available for adults only. Vitamin K is necessary for the liver to produce the coagulation factors II, VII, IX, and X, as well as the clotting factors protein C, protein S, and protein Z; vitamin K deficiency can result in deficiencies of these coagulation factors and excess bleeding. An injection of vitamin K is routinely given to newborn infants to prevent vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn. Vitamin K deficiency is rare in adults but may result from chronic malnutrition or an inability to absorb dietary vitamins. |
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NCI_PT |
Vitamin K |
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NICHD_Definition |
_ |
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prefixIRI |
Vitamin_K |
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prefLabel |
Vitamin_K |
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Subset_Association1 |
NICHD Pediatric Terminology |
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Subset_Association2 |
NICHD Newborn Screening Terminology |
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SYN | ||
subClassOf |
http://www.owl-ontologies.com/Ontology1358660052.owl#Substance |