loading...| Preferred Name | cell culture | |
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| Definitions |
A material entity comprised of cultured cells and the media in which they are being propagated or stored. a cell culture is a material entity consisting of a population of cells that is maintained in vitro A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. A cell culture includes the cells in culture, as well as the media and all additives in which the cells are being grown or in which they are stored. The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally. |
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| ID |
http://purl.obolibrary.org/obo/OBI_0001876 |
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| comment |
A cell culture includes the cells in culture, as well as the media and all additives in which the cells are being grown or in which they are stored. The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally. |
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| alternative term |
cell culture sample |
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| definition source |
OBI-CLO Alignment Working Group (Spring 2013) GROUP: OBI Biomaterial Branch PERSON:Matthew Brush |
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| editor note |
2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line. |
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| editor preferred term |
cell culture cell culture cultured cell population |
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| example of usage |
A cultured cell population applied in an experiment: "293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest." (Lee, Ramee, et al. "Regulation of cell survival by secreted proneurotrophins." Science 294.5548 (2001): 1945-1948). A cultured cell population maintained in vitro: "Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks" (Dichter, Marc A. "Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation." Brain Research 149.2 (1978): 279-293). Jurkat cell line in RPMI w/ 10% FCS. PBMCs were purified from blood sample and put into tissue culture media. Purification of recombinant human growth hormone from CHO cell culture supernatant by Gradiflow preparative electrophoresis technology. Protein Expr Purif. 2003 Nov;32(1):126-34. PMID: 14680949 |
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| label |
cell culture cell culture cultured cell population |
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| overlaps | ||
| prefixIRI |
OBI:0001876 |
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| prefLabel |
cell culture |
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| term editor |
PERSON: Bjoern Peters PERSON:Matthew Brush |
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| textual definition |
A material entity comprised of cultured cells and the media in which they are being propagated or stored. a cell culture is a material entity consisting of a population of cells that is maintained in vitro A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. |
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| disjointWith |
http://purl.obolibrary.org/obo/OBI_0100067 |
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