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Physician Data Query
| Preferred Name | imipramine | |
| Synonyms |
|
|
| Definitions |
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C62039" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C62039" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000792682 |
|
| CAS Registry |
50-49-7
|
|
| cui |
C0020934
|
|
| DATE FIRST PUBLISHED |
2018-03-19
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| Date last modified |
2018-03-19
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|
| definition |
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C62039" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C62039" NCI Thesaurus)
|
|
| NCI ID |
C62039
|
|
| notation |
CDR0000792682
|
|
| NSC Code |
169866
|
|
| ORIG STY |
Drug/agent
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|
| prefLabel |
imipramine
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|
| tui |
T109 T121
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