loading...| Preferred Name | Polymyositis | |
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| Definitions |
A rare idiopathic inflammatory myopathy (IIM) historically characterized by symmetric proximal muscle weakness, elevated muscle enzymes (creatine kinase), myopathic findings on electromyography, and muscle biopsy showing endomyial infiltration composed mainly of macrophages and lymphocytes. The features are non-specific, thus the disease should be distinguished from similar entities with specific clinical, immunological, histological features, notably dermatomyositis, immune-mediated necrotizing myopathy, anti-synthetase syndrome, inclusion body myositis, and myositis associated with other connective tissue disorder. |
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| ID |
http://www.orpha.net/ORDO/Orphanet_732 |
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| definition |
A rare idiopathic inflammatory myopathy (IIM) historically characterized by symmetric proximal muscle weakness, elevated muscle enzymes (creatine kinase), myopathic findings on electromyography, and muscle biopsy showing endomyial infiltration composed mainly of macrophages and lymphocytes. The features are non-specific, thus the disease should be distinguished from similar entities with specific clinical, immunological, histological features, notably dermatomyositis, immune-mediated necrotizing myopathy, anti-synthetase syndrome, inclusion body myositis, and myositis associated with other connective tissue disorder. |
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| definition_citation |
Orphanet |
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| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=732 |
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| has_age_of_onset |
Adult Elderly |
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| has_inheritance |
Not applicable |
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| hasDbXref |
MedDRA:10036102 ICD-11:4A41.1 MeSH:D017285 ICD-10:M33.2 UMLS:C0085655 |
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| label |
Polymyositis |
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| notation |
ORPHA:732 |
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| part_of | ||
| prefixIRI |
ORDO:Orphanet_732 |
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| prefLabel |
Polymyositis |
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| present_in |
Australia AND has_point_prevalence_average_value : 7.2 AND has_point_prevalence_range : 1-9 / 100 000 Spain AND has_annual_incidence_average_value : 0.39 AND has_annual_incidence_range : 1-9 / 1 000 000 Sweden AND has_annual_incidence_average_value : 0.76 AND has_annual_incidence_range : 1-9 / 1 000 000 Argentina AND has_annual_incidence_average_value : 0.75 AND has_annual_incidence_range : 1-9 / 1 000 000 Argentina AND has_point_prevalence_average_value : 7.2 AND has_point_prevalence_range : 1-9 / 100 000 Europe AND has_annual_incidence_average_value : 0.585 AND has_annual_incidence_range : 1-9 / 1 000 000 Europe AND has_point_prevalence_average_value : 7.1 AND has_point_prevalence_range : 1-9 / 100 000 Australia AND has_annual_incidence_average_value : 0.41 AND has_annual_incidence_range : 1-9 / 1 000 000 |
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