loading...| Preferred Name |
Gastrointestinal stromal tumor |
|
| Synonyms |
GIST |
|
| Definitions |
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal (GI) tract, typically presenting in adults over the age of 40 (mean age 63), and only rarely in children, in various regions of the GI tract, most commonly the stomach or small intestine but also less commonly in the esophagus, appendix, rectum and colon. GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass, blood in stool, and intestinal obstruction. GISTs can also be seen in familial syndromes such as Carney triad and neurofibromatosis type 1. |
|
| ID |
http://www.orpha.net/ORDO/Orphanet_44890 |
|
| alternative_term |
GIST Gastrointestinal stromal sarcoma |
|
| definition |
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal (GI) tract, typically presenting in adults over the age of 40 (mean age 63), and only rarely in children, in various regions of the GI tract, most commonly the stomach or small intestine but also less commonly in the esophagus, appendix, rectum and colon. GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass, blood in stool, and intestinal obstruction. GISTs can also be seen in familial syndromes such as Carney triad and neurofibromatosis type 1. |
|
| definition_citation |
Orphanet |
|
| expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=44890 |
|
| has_age_of_onset |
Adolescent Adult Childhood |
|
| has_inheritance |
Not applicable Autosomal dominant |
|
| hasDbXref |
MeSH:D046152 ICD-10:C26.9 OMIM:175510 ICD-11:2B5B OMIM:606764 UMLS:C0238198 ICD-11:XH9HQ1 MedDRA:10051066 |
|
| label |
Gastrointestinal stromal tumor |
|
| notation |
ORPHA:44890 |
|
| part_of | ||
| prefixIRI |
ORDO:Orphanet_44890 |
|
| prefLabel |
Gastrointestinal stromal tumor |
|
| present_in |
Europe AND has_point_prevalence_average_value : 13.0 AND has_point_prevalence_range : 1-5 / 10 000 Europe AND has_annual_incidence_average_value : 1.0 AND has_annual_incidence_range : 1-9 / 100 000 Sweden AND has_point_prevalence_average_value : 12.9 AND has_point_prevalence_range : 1-5 / 10 000 Worldwide AND has_annual_incidence_average_value : 1.0 AND has_annual_incidence_range : 1-9 / 100 000 Korea, Republic of AND has_annual_incidence_average_value : 1.9 AND has_annual_incidence_range : 1-9 / 100 000 United States AND has_annual_incidence_average_value : 1.5 AND has_annual_incidence_range : 1-9 / 100 000 Hong Kong AND has_point_prevalence_average_value : 14.5 AND has_point_prevalence_range : 1-5 / 10 000 Hong Kong AND has_annual_incidence_average_value : 1.82 AND has_annual_incidence_range : 1-9 / 100 000 |
|
| treeView | ||
| subClassOf |