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Orphanet Rare Disease Ontology
Last uploaded:
July 3, 2024
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Preferred Name | Multiple myeloma | |
Synonyms |
Medullary plasmacytoma Kahler disease Myelomatosis Plasma cell myeloma |
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Definitions |
Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig). |
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ID |
http://www.orpha.net/ORDO/Orphanet_29073 |
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alternative_term |
Medullary plasmacytoma Kahler disease Myelomatosis Plasma cell myeloma
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definition |
Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).
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definition_citation |
Orphanet
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expertlink |
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=en&Expert=29073 |
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has_age_of_onset |
Adult
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has_inheritance |
Not applicable
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hasDbXref |
OMIM:254500 ICD-10:C90.0 ICD-11:2A83.1 MedDRA:10028228 MeSH:D009101 UMLS:C0026764
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label |
Multiple myeloma
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notation |
ORPHA:29073
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part_of | ||
prefixIRI |
ORDO:Orphanet_29073
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prefLabel |
Multiple myeloma
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present_in |
Europe AND has_point_prevalence_average_value : 11.9 AND has_point_prevalence_range : 1-5 / 10 000 Australia AND has_annual_incidence_average_value : 5.1 AND has_annual_incidence_range : 1-9 / 100 000 United States AND has_birth_prevalence_average_value : 3.8 AND has_birth_prevalence_range : 1-9 / 100 000 France AND has_annual_incidence_average_value : 7.7 AND has_annual_incidence_range : 1-9 / 100 000 Denmark AND has_annual_incidence_average_value : 6.2 AND has_annual_incidence_range : 1-9 / 100 000 Worldwide AND has_annual_incidence_average_value : 6.0 AND has_annual_incidence_range : 1-9 / 100 000 Europe AND has_annual_incidence_average_value : 2.4 AND has_annual_incidence_range : 1-9 / 100 000 United States AND has_annual_incidence_average_value : 5.6 AND has_annual_incidence_range : 1-9 / 100 000 Iran, Islamic Republic of AND has_annual_incidence_average_value : 2.0 AND has_annual_incidence_range : 1-9 / 100 000
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