loading...| Preferred Name |
Parkinsons disease |
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| Synonyms |
Parkinson's syndrome Parkinson disease Parkinson syndrome Paralysis Agitans Idiopathic PD Parkinson's Parkinson's disease Parkinsonian disorder Parkinsons |
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| ID |
http://uri.neuinfo.org/nif/nifstd/birnlex_2098 |
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| acronym |
PD |
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| birnlexDefinition |
* A disease characterized as a progressive motor disability manifested by tremors, shaking, muscular rigidity, and lack of postural reflexes. (PSY) * A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) (MSH) * progressive, degenerative disorder of the nervous system characterized by tremors, rigidity, bradykinesia, postural instability, and gait abnormalities; caused by a loss of neurons and a decrease of dopamine in the basal ganglia. (CSP) |
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| createdDate |
2007-03-05 |
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| definingCitationURI |
http://www.ninds.nih.gov/disorders/parkinsons_disease/parkinsons_disease.htm |
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| hasBirnlexCurator | ||
| hasDefinitionSource | ||
| label |
Parkinsons disease |
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| modifiedDate |
June 24, 2009 |
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| nifID |
_8.3_2.7 |
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| preferred label |
Parkinsons disease |
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| putativeClassExtension |
Primary Parkinsonism Lewy Body Parkinson Disease Idiopathic Parkinson Disease |
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| synonym |
Parkinson's syndrome Parkinson disease Parkinson syndrome Paralysis Agitans Idiopathic PD Parkinson's Parkinson's disease Parkinsonian disorder Parkinsons |
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| UmlsCui |
C0030567 |
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| usageNote |
MeSH includes several implied subtypes based primarily on causation |
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| subClassOf |
http://purl.obolibrary.org/obo/DOID_1289 |