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Neuroscience Information Framework (NIF) Standard Ontology
Last uploaded:
February 10, 2018
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| Preferred Name | Myasthenia Gravis | |
| Synonyms |
Myasthenia Gravis, Generalized |
|
| Definitions |
A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition (MeSH). |
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| ID |
http://uri.neuinfo.org/nif/nifstd/birnlex_12593 |
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| alternative label |
Myasthenia Gravis, Generalized
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|
| createdDate |
2007-10-05
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|
| definingCitation |
Adams et al., Principles of Neurology, 6th ed, p1459
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| definingCitationURI |
http://www.ninds.nih.gov/disorders/myasthenia_gravis/myasthenia_gravis.htm |
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| definition |
A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition (MeSH).
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| editorial note | ||
| externalSourceId |
D009157 _8.3_9.1
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| hasBirnlexCurator | ||
| hasCurationStatus | ||
| hasDefinitionSource | ||
| hasExternalSource | ||
| label |
Myasthenia Gravis
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| MeshUid |
D009157
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|
| modifiedDate |
2007-10-05
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| nifID |
_8.3_9.1
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|
| note |
A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition (MeSH).
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|
| preferred label |
Myasthenia Gravis
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|
| Resource Identifier |
D009157 _8.3_9.1
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|
| synonym |
Myasthenia Gravis, Generalized
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| subClassOf |
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