Preferred Name

Astrocytoma

Synonyms
Definitions

Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation (MeSH).

ID

http://uri.neuinfo.org/nif/nifstd/birnlex_12619

createdDate

2007-10-05

definingCitation

Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082

definition

Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation (MeSH).

hasBirnlexCurator

http://uri.neuinfo.org/nif/nifstd/readable/Bill_Bug

hasCurationStatus

http://uri.neuinfo.org/nif/nifstd/readable/uncurated

hasDefinitionSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH_defSource

hasExternalSource

http://uri.neuinfo.org/nif/nifstd/readable/MeSH

label

Astrocytoma

MeshUid

D001254

modifiedDate

2007-10-05

preferred label

Astrocytoma

scope note

Grades I-III go here, with pathol

synonym

Astrocytic Glioma

Astroglioma

usageNote

The following Entry Terms in MeSH imply a series of sub-types based on anatomical location, developmental onset, histological profile, and neoplastic state: Astrocytoma, Grade I; Astrocytoma, Grade II; Astrocytoma, Grade III; Astrocytoma, Protoplasmic; Astrocytoma, Subependymal Giant Cell; Cerebral Astrocytoma; Childhood Cerebral Astrocytoma; Fibrillary Astrocytoma; Gemistocytic Astrocytoma; Intracranial Astrocytoma; Juvenile Pilocytic Astrocytoma; Oligoastrocytoma, Mixed; Pilocytic Astrocytoma; Subependymal Giant Cell Astrocytoma

subClassOf

http://uri.neuinfo.org/nif/nifstd/birnlex_12600

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Delete Mapping To Ontology Source
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