loading...| Preferred Name |
Vitamin K |
|
| Synonyms |
2-methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)naphthalene-1,4-dione Vitamin K vitamin K |
|
| Definitions |
The term "vitamin K" refers to a group of chemically similar fat-soluble compounds called naphthoquinones: vitamin K1 (phytonadione) is found in plants and is the primary source of vitamin K for humans through dietary consumption, vitamin K2 compounds (menaquinones) are made by bacteria in the human gut, and vitamin K3 (menadione) is a water-soluble preparation available for adults only. Vitamin K is necessary for the liver to produce the coagulation factors II, VII, IX, and X, as well as the clotting factors protein C, protein S, and protein Z; vitamin K deficiency can result in deficiencies of these coagulation factors and excess bleeding. An injection of vitamin K is routinely given to newborn infants to prevent vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn. Vitamin K deficiency is rare in adults but may result from chronic malnutrition or an inability to absorb dietary vitamins. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C943 |
|
| ALT_DEFINITION |
Fat soluble vitamin that is a coenzyme during the synthesis of the biologically active form of a number of proteins involved in blood coagulation and bone metabolism. Vitamin K's structure typically consists of a methylated naphthoquinone ring from which one or more unsaturated aliphatic side chains are attached at the 3-position of the ring. A nutrient that the body needs in small amounts to function and stay healthy. Vitamin K helps to form blood clots (a mass that forms when blood platelets, proteins, and cells stick together) and maintain strong bones. It is fat-soluble (can dissolve in fats and oils) and is found in green leafy vegetables, broccoli, liver, and vegetable oils. Vitamin K is also made by bacteria that live in the large intestine. Not enough vitamin K can lead to bleeding and bruising. |
|
| CAS_Registry |
12001-79-5 |
|
| CHEBI_ID |
CHEBI:28384 |
|
| Chemical_Formula |
C31H46O2 |
|
| code |
C943 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C89506 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 |
|
| Contributing_Source |
CRCH CTRP NICHD |
|
| DEFINITION |
The term "vitamin K" refers to a group of chemically similar fat-soluble compounds called naphthoquinones: vitamin K1 (phytonadione) is found in plants and is the primary source of vitamin K for humans through dietary consumption, vitamin K2 compounds (menaquinones) are made by bacteria in the human gut, and vitamin K3 (menadione) is a water-soluble preparation available for adults only. Vitamin K is necessary for the liver to produce the coagulation factors II, VII, IX, and X, as well as the clotting factors protein C, protein S, and protein Z; vitamin K deficiency can result in deficiencies of these coagulation factors and excess bleeding. An injection of vitamin K is routinely given to newborn infants to prevent vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn. Vitamin K deficiency is rare in adults but may result from chronic malnutrition or an inability to absorb dietary vitamins. |
|
| Display_Name |
Vitamin K |
|
| FULL_SYN |
2-methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)naphthalene-1,4-dione Vitamin K vitamin K |
|
| INFOODS |
VITK |
|
| label |
Vitamin K |
|
| Legacy Concept Name |
Vitamin_K |
|
| Micronutrient |
Y |
|
| NCI_Drug_Dictionary_ID |
786611 |
|
| Nutrient |
Y |
|
| PDQ_Closed_Trial_Search_ID |
786611 |
|
| PDQ_Open_Trial_Search_ID |
786611 |
|
| Preferred_Name |
Vitamin K |
|
| prefixIRI |
Thesaurus:C943 |
|
| Semantic_Type |
Vitamin |
|
| UMLS_CUI |
C0042878 |
|
| Unit |
mcg |
|
| US_Recommended_Intake |
Y |
|
| USDA_ID |
430 |
|
| subClassOf |