loading...| Preferred Name |
Serum Sickness |
|
| Synonyms |
Serum Sickness Serum sickness |
|
| Definitions |
Delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest pain, and dyspnea. Certain drugs (e.g., antibiotics, anticancer agents, and anti-inflammatory medications) and infectious disorders (e.g., hepatitis B) may also cause serum sickness-like reaction. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C79718 |
|
| ALT_DEFINITION |
A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea. A systemic, immune complex mediated hypersensitivity reaction to injected foreign or autologous protein that usually presents four to ten days after exposure and resolves on its own. Manifestations may include fever, joint pain, rash, and swollen lymph nodes. |
|
| code |
C79718 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 |
|
| Contributing_Source |
MedDRA NICHD |
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| DEFINITION |
Delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest pain, and dyspnea. Certain drugs (e.g., antibiotics, anticancer agents, and anti-inflammatory medications) and infectious disorders (e.g., hepatitis B) may also cause serum sickness-like reaction. |
|
| FULL_SYN |
Serum Sickness Serum sickness |
|
| label |
Serum Sickness |
|
| Legacy Concept Name |
Serum_Sickness |
|
| Maps_To |
Serum sickness |
|
| Preferred_Name |
Serum Sickness |
|
| prefixIRI |
Thesaurus:C79718 |
|
| Semantic_Type |
Disease or Syndrome |
|
| UMLS_CUI |
C0036830 |
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| subClassOf |