loading...| Preferred Name |
Type IV Hypersensitivity |
|
| Synonyms |
Delayed-Type Hypersensitivity delayed-type hypersensitivity response Type 4 Hypersensitivity Reaction Delayed-Type Hypersensitivity Response Delayed Hypersensitivity Reaction Type IV Hypersensitivity Type IV Hypersensitivity Reaction DTH |
|
| Definitions |
Delayed hypersensitivity reaction (DTH) - type IV reaction, an inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. DTH is mediated by T cells rather than by antibodies. Th1 cells produce interferon gamma, interleukin (IL)-2, and tumor necrosis factor-beta and promote a cell-mediated immune response. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3115 |
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| ALT_DEFINITION |
An inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. This type of immune response involves mainly T cells rather than antibodies (which are made by B cells). A hypersensitivity reaction triggered by sensitized T lymphocytes encountering antigens. These reactions usually develop 18 to 24 hours after exposure. |
|
| code |
C3115 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
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| Contributing_Source |
CTRP MedDRA NICHD |
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| DEFINITION |
Delayed hypersensitivity reaction (DTH) - type IV reaction, an inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. DTH is mediated by T cells rather than by antibodies. Th1 cells produce interferon gamma, interleukin (IL)-2, and tumor necrosis factor-beta and promote a cell-mediated immune response. |
|
| Display_Name |
Type IV Hypersensitivity |
|
| FULL_SYN |
Delayed-Type Hypersensitivity delayed-type hypersensitivity response Type 4 Hypersensitivity Reaction Delayed-Type Hypersensitivity Response Delayed Hypersensitivity Reaction Type IV Hypersensitivity Type IV Hypersensitivity Reaction DTH |
|
| label |
Type IV Hypersensitivity |
|
| Legacy Concept Name |
Delayed-Type_Hypersensitivity |
|
| Maps_To |
Type IV hypersensitivity reaction |
|
| Preferred_Name |
Type IV Hypersensitivity |
|
| prefixIRI |
Thesaurus:C3115 |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0020522 |
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| subClassOf |