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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Imipramine | |
| Synonyms |
5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro- IMIPRAMINE Imipramine |
|
| Definitions |
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62039 |
|
| CAS_Registry |
50-49-7
|
|
| CHEBI_ID |
CHEBI:47499
|
|
| Chemical_Formula |
C19H24N2
|
|
| code |
C62039
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04)
|
|
| FDA_UNII_Code |
OGG85SX4E4
|
|
| FULL_SYN |
5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro- IMIPRAMINE Imipramine
|
|
| Has_Salt_Form | ||
| label |
Imipramine
|
|
| Legacy Concept Name |
Imipramine_Base
|
|
| NCI_Drug_Dictionary_ID |
792682
|
|
| NSC Number |
169866
|
|
| PDQ_Closed_Trial_Search_ID |
792682
|
|
| PDQ_Open_Trial_Search_ID |
792682
|
|
| Preferred_Name |
Imipramine
|
|
| prefixIRI |
Thesaurus:C62039
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0020934
|
|
| subClassOf |
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