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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Bupropion | |
| Synonyms |
1-Propanone, 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)- Amfebutamon BUPROPION Bupropion bupropion |
|
| Definitions |
An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62012 |
|
| ALT_DEFINITION |
A substance that is used to treat depression, and to help people quit smoking. It belongs to the family of drugs called antidepressants.
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|
| CAS_Registry |
34911-55-2
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|
| CHEBI_ID |
CHEBI:3219
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|
| Chemical_Formula |
C13H18ClNO
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|
| code |
C62012
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
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|
| DEFINITION |
An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine.
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|
| Display_Name |
Bupropion
|
|
| FDA_UNII_Code |
01ZG3TPX31
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|
| FULL_SYN |
1-Propanone, 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)- Amfebutamon BUPROPION Bupropion bupropion
|
|
| Has_Salt_Form |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74947 |
|
| label |
Bupropion
|
|
| Legacy Concept Name |
Bupropion_Base
|
|
| Preferred_Name |
Bupropion
|
|
| prefixIRI |
Thesaurus:C62012
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0085208
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|
| subClassOf |
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