National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Choline
Synonyms

2-hydroxyethyl-trimethyl-ammonium

(2-Hydroxyethyl)trimethylammonium

CHOLINE

Choline

Vitamin J

choline

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61674

ALT_DEFINITION

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Choline helps cells make membranes, make a neurotransmitter (a chemical that helps nerve cells communicate with other cells), and remove fat from the liver. It is found in whole milk, beef liver, eggs, soy foods, and peanuts. Choline is water-soluble (can dissolve in water) and must be taken in every day. Not enough choline can cause diseases of the heart and blood vessels and damage to the liver. A form of choline is being studied in the treatment of some types of cancer and to reduce pain and fever. Choline is also being studied together with vitamin B12 in the prevention and treatment of cancer.

Water-soluble vitamin that is a precursor for acetylcholine, phospholipids, and the methyl donor betaine. (DRI)

CAS_Registry

62-49-7

CHEBI_ID

CHEBI:15354

Chemical_Formula

C5H14NO

code

C61674

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CRCH

CTRP

FDA

GDC

Display_Name

Choline

FDA_UNII_Code

N91BDP6H0X

FULL_SYN

2-hydroxyethyl-trimethyl-ammonium

(2-Hydroxyethyl)trimethylammonium

CHOLINE

Choline

Vitamin J

choline

INFOODS

CHOLN

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2480

label

Choline

Legacy Concept Name

Choline

Maps_To

Choline

Micronutrient

Y

Nutrient

Y

Preferred_Name

Choline

prefixIRI

Thesaurus:C61674

Semantic_Type

Vitamin

Tolerable_Level

Y

UMLS_CUI

C0008405

Unit

mcg

US_Recommended_Intake

Y

USDA_ID

421

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1551

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_15354 DRON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.877.883.333 RH-MESH LOOM
http://purl.jp/bio/4/id/200906097406502953 IOBC LOOM
http://doe-generated-ontology.com/OntoAD#C0008405 ONTOAD LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 CARO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 UBERON LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 ONSTR LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 MAXO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_15354 OBA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.063.291.211 RH-MESH LOOM
http://purl.obolibrary.org/obo/dinto_DB00122 DINTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.675.276.232 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146071 NDFRT LOOM
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Choline PCAO LOOM
http://purl.obolibrary.org/obo/MESH_D002794 BERO LOOM
http://www.bioontology.org/pma.owl#PMA_1559 PMA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002794 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4017699 VANDF LOOM
https://go.drugbank.com/drugs/DB00122 MDM LOOM
http://purl.obolibrary.org/obo/UPa_UPC00114 UPA LOOM
http://purl.bioontology.org/ontology/SNMI/F-61620 SNMI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008405 OCHV LOOM
http://www.co-ode.org/ontologies/galen#Choline GALEN LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015636 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/CSP/0663-0420 CRISP LOOM
http://www.projecthalo.com/aura#Choline AURA LOOM
http://purl.bioontology.org/ontology/RXNORM/2449 RXNORM LOOM
http://purl.obolibrary.org/obo/NCIT_C61674 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D002794 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.033.100.291.211 RH-MESH LOOM
http://www.semanticweb.org/ADMO#Choline ADMO LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Choline APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Choline APAONTO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2888 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0004114 OMIT LOOM
http://purl.bioontology.org/ontology/RCD/Ub08Y RCD LOOM
http://stirdf.jst.go.jp/id/200907025661687641 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/65123005 SNOMEDCT LOOM
https://www.fns-cloud.eu/foodComponents/FNS_H_0000003063 FNS-H LOOM