National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

N-Nitrosodimethylamine

Synonyms

N-NITROSODIMETHYLAMINE

Dimethylnitrosamine

N-Nitrosodimethylamine

N-Methyl-N-nitrosomethanamine

DMN

DMNA

NDMA

Definitions

A volatile, combustible, yellow, oily liquid nitrosamine with a faint characteristic odor that decomposes when exposed to light and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosodimethylamine is primarily used in laboratory research to induce tumors in experimental animals. This substance may be formed during the cooking of foods, especially cured meats and fish, that contain sodium nitrite as a preservative, but is also found in several vegetables, cheeses, alcoholic beverages and fruits, and as a contaminant in rubber products. Exposure to NNitrosodimethylamine irritates the skin and eyes and damages the liver. This substance is reasonably anticipated to be a human carcinogen. (NCI05)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C44417

CAS_Registry

62-75-9

CHEBI_ID

CHEBI:35807

Chemical_Formula

C2H6N2O

code

C44417

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A volatile, combustible, yellow, oily liquid nitrosamine with a faint characteristic odor that decomposes when exposed to light and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosodimethylamine is primarily used in laboratory research to induce tumors in experimental animals. This substance may be formed during the cooking of foods, especially cured meats and fish, that contain sodium nitrite as a preservative, but is also found in several vegetables, cheeses, alcoholic beverages and fruits, and as a contaminant in rubber products. Exposure to NNitrosodimethylamine irritates the skin and eyes and damages the liver. This substance is reasonably anticipated to be a human carcinogen. (NCI05)

FDA_UNII_Code

M43H21IO8R

FULL_SYN

N-NITROSODIMETHYLAMINE

Dimethylnitrosamine

N-Nitrosodimethylamine

N-Methyl-N-nitrosomethanamine

DMN

DMNA

NDMA

label

N-Nitrosodimethylamine

Legacy Concept Name

N-Nitrosodimethylamine

NSC Number

23226

Preferred_Name

N-Nitrosodimethylamine

prefixIRI

Thesaurus:C44417

Semantic_Type

Hazardous or Poisonous Substance

UMLS_CUI

C0012431

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45398

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