Preferred Name |
Medulloblastoma |
|
Synonyms |
MEDULLOBLASTOMA, MALIGNANT CNS, medulloblastoma Medulloblastoma medulloblastoma Medulloblastomas |
|
Definitions |
A malignant, invasive embryonal neoplasm arising from the cerebellum or posterior fossa. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3222 |
|
ALT_DEFINITION |
A malignant, invasive embryonal neoplasm arising from the cerebellum. A malignant brain tumor that begins in the lower part of the brain and that can spread to the spine or to other parts of the body. Medulloblastomas are a type of primitive neuroectodermal tumor (PNET). A rapidly progressive cancer of the brain that originates in the cerebellum. |
|
code |
C3222 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C88025 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C102905 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C189762 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C103046 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118464 |
|
Contributing_Source |
Cellosaurus CDISC CTEP GDC MedDRA NICHD |
|
DEFINITION |
A malignant, invasive embryonal neoplasm arising from the cerebellum or posterior fossa. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity. |
|
FULL_SYN |
MEDULLOBLASTOMA, MALIGNANT CNS, medulloblastoma Medulloblastoma medulloblastoma Medulloblastomas |
|
ICD-O-3_Code |
9470/3 |
|
Is_Value_For_GDC_Property | ||
label |
Medulloblastoma |
|
Legacy Concept Name |
Medulloblastoma |
|
Maps_To |
CNS, medulloblastoma Medulloblastoma |
|
Neoplastic_Status |
Malignant |
|
Preferred_Name |
Medulloblastoma |
|
prefixIRI |
Thesaurus:C3222 |
|
Semantic_Type |
Neoplastic Process |
|
UMLS_CUI |
C0025149 |
|
subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C170814 |