loading...| Preferred Name | Celiac Disease | |
| Synonyms |
Non Tropical Sprue Celiac Sprue Gluten-Induced Enteropathy celiac disease Celiac Disease |
|
| Definitions |
An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26714 |
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| ALT_DEFINITION |
A digestive disease that is caused by an immune response to a protein called gluten, which is found in wheat, rye, barley, and oats. Celiac disease damages the lining of the small intestine and interferes with the absorption of nutrients from food. A person with celiac disease may become malnourished no matter how much food is consumed. |
|
| code |
C26714 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C186315 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192842 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C165258 |
|
| Contributing_Source |
Cellosaurus GDC PCDC |
|
| DEFINITION |
An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. |
|
| FULL_SYN |
Non Tropical Sprue Celiac Sprue Gluten-Induced Enteropathy celiac disease Celiac Disease |
|
| Is_Value_For_GDC_Property | ||
| label |
Celiac Disease |
|
| Legacy Concept Name |
Celiac_Disease |
|
| Maps_To |
Celiac Disease |
|
| Preferred_Name |
Celiac Disease |
|
| prefixIRI |
Thesaurus:C26714 |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0007570 |
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| subClassOf |