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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Dexmethylphenidate | |
| Synonyms |
Dexmethylphenidate dexmethylphenidate DEXMETHYLPHENIDATE |
|
| Definitions |
The d-threo-enantiomer of methylphenidate, a central nervous system stimulant, appearing to block the reuptake of norepinephrine and dopamine into the presynaptic neuron, increasing their availability in the extracellular space. The mechanism of action in Attention Deficit Hyperactivity Disorder is unknown. (NCI) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26642 |
|
| Accepted_Therapeutic_Use_For |
Attention Deficit Hyperactivity Disorder.
|
|
| ALT_DEFINITION |
A substance being studied in the treatment of fatigue and nervous system side effects caused by chemotherapy. It is a type of central nervous system stimulant.
|
|
| CAS_Registry |
40431-64-9
|
|
| Chemical_Formula |
C14H19NO2
|
|
| code |
C26642
|
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
|
|
| DEFINITION |
The d-threo-enantiomer of methylphenidate, a central nervous system stimulant, appearing to block the reuptake of norepinephrine and dopamine into the presynaptic neuron, increasing their availability in the extracellular space. The mechanism of action in Attention Deficit Hyperactivity Disorder is unknown. (NCI)
|
|
| FDA_UNII_Code |
M32RH9MFGP
|
|
| FULL_SYN |
Dexmethylphenidate dexmethylphenidate DEXMETHYLPHENIDATE
|
|
| Has_Salt_Form | ||
| label |
Dexmethylphenidate
|
|
| Legacy Concept Name |
Dexmethylphenidate
|
|
| NCI_Drug_Dictionary_ID |
269067
|
|
| PDQ_Closed_Trial_Search_ID |
269067
|
|
| PDQ_Open_Trial_Search_ID |
269067
|
|
| Preferred_Name |
Dexmethylphenidate
|
|
| prefixIRI |
Thesaurus:C26642
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C1169997
|
|
| subClassOf |
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