Medical Subject Headings

Last uploaded: January 16, 2025

Preferred Name	Mitomycin
Synonyms	Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))- Mitomycin-C Mitocin-C NSC26980 Mitomycin C Mitocin C MitocinC NSC-26980 NSC 26980 Ametycine Mutamycin
Definitions	An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
ID	http://purl.bioontology.org/ontology/MESH/D016685
altLabel	Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))- Mitomycin-C Mitocin-C NSC26980 Mitomycin C Mitocin C MitocinC NSC-26980 NSC 26980 Ametycine Mutamycin
AN	MITOMYCINS is also available
AQL	AD AE AG AI AN BI BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0702049 C0702048 C0002475 C0702051 C0702050
DC	1
definition	An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
DX	19920101
EC	analogs & derivatives:Mitomycins
HN	2000(1992); for MITOMYCIN use MITOMYCIN (NM) 1981-1991
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	50SG953SK6 0
isa	http://purl.bioontology.org/ontology/MESH/D000477 http://purl.bioontology.org/ontology/MESH/D000903 http://purl.bioontology.org/ontology/MESH/D003432 http://purl.bioontology.org/ontology/MESH/D019384
LT	TRD
Machine permutation	2000; see MITOMYCIN C 1992-1999; MITOMYCIN C was indexed under MITOMYCINS 1981-1990
Mapped from	http://purl.bioontology.org/ontology/MESH/C053713 http://purl.bioontology.org/ontology/MESH/C051113 http://purl.bioontology.org/ontology/MESH/C048473 http://purl.bioontology.org/ontology/MESH/C075608 http://purl.bioontology.org/ontology/MESH/C046104 http://purl.bioontology.org/ontology/MESH/C034908 http://purl.bioontology.org/ontology/MESH/C071758 http://purl.bioontology.org/ontology/MESH/C034852 http://purl.bioontology.org/ontology/MESH/C092462 http://purl.bioontology.org/ontology/MESH/C063755 http://purl.bioontology.org/ontology/MESH/C101920 http://purl.bioontology.org/ontology/MESH/C061718 http://purl.bioontology.org/ontology/MESH/C031179 http://purl.bioontology.org/ontology/MESH/C110432 http://purl.bioontology.org/ontology/MESH/C044586 http://purl.bioontology.org/ontology/MESH/C040597 http://purl.bioontology.org/ontology/MESH/C035931 http://purl.bioontology.org/ontology/MESH/C038386 http://purl.bioontology.org/ontology/MESH/C073578 http://purl.bioontology.org/ontology/MESH/C494068 http://purl.bioontology.org/ontology/MESH/C064470 http://purl.bioontology.org/ontology/MESH/C102420 http://purl.bioontology.org/ontology/MESH/C092984 http://purl.bioontology.org/ontology/MESH/C044627 http://purl.bioontology.org/ontology/MESH/C052012 http://purl.bioontology.org/ontology/MESH/C056417 http://purl.bioontology.org/ontology/MESH/C473651 http://purl.bioontology.org/ontology/MESH/C081152 http://purl.bioontology.org/ontology/MESH/C400981 http://purl.bioontology.org/ontology/MESH/C057922 http://purl.bioontology.org/ontology/MESH/C091469 http://purl.bioontology.org/ontology/MESH/C110661 http://purl.bioontology.org/ontology/MESH/C448581 http://purl.bioontology.org/ontology/MESH/C038337 http://purl.bioontology.org/ontology/MESH/C401501 http://purl.bioontology.org/ontology/MESH/C043623 http://purl.bioontology.org/ontology/MESH/C445781 http://purl.bioontology.org/ontology/MESH/C090513 http://purl.bioontology.org/ontology/MESH/C109675 http://purl.bioontology.org/ontology/MESH/C049560 http://purl.bioontology.org/ontology/MESH/C068487 http://purl.bioontology.org/ontology/MESH/C066689 http://purl.bioontology.org/ontology/MESH/C040961 http://purl.bioontology.org/ontology/MESH/C034645 http://purl.bioontology.org/ontology/MESH/C084946 http://purl.bioontology.org/ontology/MESH/C069519 http://purl.bioontology.org/ontology/MESH/C099914 http://purl.bioontology.org/ontology/MESH/C037504 http://purl.bioontology.org/ontology/MESH/C056589 http://purl.bioontology.org/ontology/MESH/C072043 http://purl.bioontology.org/ontology/MESH/C095423 http://purl.bioontology.org/ontology/MESH/C037053 http://purl.bioontology.org/ontology/MESH/C078351 http://purl.bioontology.org/ontology/MESH/C078350 http://purl.bioontology.org/ontology/MESH/C061906 http://purl.bioontology.org/ontology/MESH/C054153 http://purl.bioontology.org/ontology/MESH/C118836 http://purl.bioontology.org/ontology/MESH/C042774 http://purl.bioontology.org/ontology/MESH/C042383 http://purl.bioontology.org/ontology/MESH/C054569 http://purl.bioontology.org/ontology/MESH/C403590 http://purl.bioontology.org/ontology/MESH/C465007 http://purl.bioontology.org/ontology/MESH/C045098 http://purl.bioontology.org/ontology/MESH/C042790 http://purl.bioontology.org/ontology/MESH/C035929 http://purl.bioontology.org/ontology/MESH/C039908 http://purl.bioontology.org/ontology/MESH/C063337 http://purl.bioontology.org/ontology/MESH/C066787 http://purl.bioontology.org/ontology/MESH/C038450 http://purl.bioontology.org/ontology/MESH/C055427 http://purl.bioontology.org/ontology/MESH/C041860 http://purl.bioontology.org/ontology/MESH/C068976 http://purl.bioontology.org/ontology/MESH/C049048 http://purl.bioontology.org/ontology/MESH/C035955
MDA	19910125
MMR	20190701
MN	D03.633.100.473.412.249.350 D03.383.097.500.350 D02.806.400.249.350
notation	D016685
PA	D000477 D019384 D000903 D003432
prefLabel	Mitomycin
RR	69515-74-8 ((1aalpha,8beta,8aalpha,8balpha)-isomer) 50-07-7 (Mitomycin)
TERMUI	T049976 T049977 T049980 T049978 T049979 T049981 T026710
TH	USAN (1972) FDA SRS (2014) JAN (19XX) NLM (1992) INN (19XX) USP (19XX) BAN (19XX)
tui	T109 T195
subClassOf	http://purl.bioontology.org/ontology/MESH/D008937

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/PDQ/CDR0000042674	PDQ	CUI
http://purl.bioontology.org/ontology/MSHFRE/D016685	MSHFRE	CUI
http://purl.bioontology.org/ontology/SCTSPA/387331000	SCTSPA	CUI
http://purl.bioontology.org/ontology/SNMI/C-C1EB0	SNMI	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042674	PDQ	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042674	PDQ	CUI
http://purl.bioontology.org/ontology/RCD/h25..	RCD	CUI
http://purl.bioontology.org/ontology/NDDF/002660	NDDF	CUI
http://purl.bioontology.org/ontology/ATC/L01DC03	ATC	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006570	NDFRT	CUI
http://purl.bioontology.org/ontology/SCTSPA/59240002	SCTSPA	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146471	NDFRT	CUI
http://purl.bioontology.org/ontology/SNMI/C-78190	SNMI	CUI
http://purl.bioontology.org/ontology/CSP/0201-5348	CRISP	CUI
http://purl.bioontology.org/ontology/CSP/0201-5348	CRISP	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042674	PDQ	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042674	PDQ	CUI
http://purl.bioontology.org/ontology/RXNORM/632	RXNORM	CUI
http://purl.bioontology.org/ontology/VANDF/4018134	VANDF	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/59240002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387331000	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D016685	MSHFRE	CUI
http://purl.bioontology.org/ontology/RXNORM/204298	RXNORM	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000042674	PDQ	CUI
http://purl.bioontology.org/ontology/RCD/h25..	RCD	LOOM
http://purl.bioontology.org/ontology/NDDF/002660	NDDF	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0026254	OCHV	LOOM
http://www.co-ode.org/ontologies/galen#Mitomycin	GALEN	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.473.412.249.350	RH-MESH	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1820	NCIT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1820	ROO	LOOM
http://purl.bioontology.org/ontology/ATC/L01DC03	ATC	LOOM
http://purl.bioontology.org/ontology/CSP/0201-3475	CRISP	LOOM
http://purl.bioontology.org/ontology/CSP/0201-3475	CRISP	LOOM
http://purl.obolibrary.org/obo/MESH_D016685	BERO	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146471	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-78190	SNMI	LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_25357	NPO	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0002475	HFO	LOOM
http://purl.obolibrary.org/obo/OMIT_0017139	OMIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C1820	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D016685	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	FB-CV	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	PECO	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	FYPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_25357	MCO	LOOM
http://purl.bioontology.org/ontology/RXNORM/632	RXNORM	LOOM
rgo:15185	GAMUTS	LOOM
http://purl.bioontology.org/ontology/VANDF/4018134	VANDF	LOOM
http://purl.jp/bio/4/id/200906099527722228	IOBC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002475	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.806.400.249.350	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.097.500.350	RH-MESH	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387331000	SNOMEDCT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017356	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/dinto_DB00305	DINTO	LOOM
https://go.drugbank.com/drugs/DB00305	MDM	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#999	OCHV	LOOM