loading...| Preferred Name | Thyroxine | |
| Synonyms |
Sodium Levothyroxine O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine L Thyrox Levothroid L Thyroxine Novothyrox O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine Levothyroxin Deladande L-3,5,3',5'-Tetraiodothyronine Levo-T Lévothyrox Levoxyl Tiroidine Levoxine Levothyroid Eutirox L-Thyrox Thyroxin Novothyral Oroxine Thevier L Thyroxine Roche L-Thyroxin beta Levothyroxine Synthrox Levothyroxin Delalande L-Thyroxine L Thyroxin Henning Tiroxina Leo Levo T L-Thyroxin Henning Eltroxin L Thyroxin beta Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo- Unithroid Eltroxine Berlthyrox Thyroid Hormone, T4 Levothyroxine Sodium Synthroid 3,5,3',5'-Tetraiodothyronine Eferox T4 Thyroid Hormone Euthyrox Dexnon L-Thyroxine Roche Thyrax |
|
| Definitions |
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D013974 |
|
| altLabel |
Sodium Levothyroxine O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine L Thyrox Levothroid L Thyroxine Novothyrox O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine Levothyroxin Deladande L-3,5,3',5'-Tetraiodothyronine Levo-T Lévothyrox Levoxyl Tiroidine Levoxine Levothyroid Eutirox L-Thyrox Thyroxin Novothyral Oroxine Thevier L Thyroxine Roche L-Thyroxin beta Levothyroxine Synthrox Levothyroxin Delalande L-Thyroxine L Thyroxin Henning Tiroxina Leo Levo T L-Thyroxin Henning Eltroxin L Thyroxin beta Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo- Unithroid Eltroxine Berlthyrox Thyroid Hormone, T4 Levothyroxine Sodium Synthroid 3,5,3',5'-Tetraiodothyronine Eferox T4 Thyroid Hormone Euthyrox Dexnon L-Thyroxine Roche Thyrax |
|
| AN |
/blood: consider also HYPERTHYROXINEMIA |
|
| AQL |
AA AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UR |
|
| cui |
C0939521 C0591440 C1450024 C1450015 C0733607 C1450025 C1450013 C0733848 C1450023 C0721345 C0040165 C0733849 C1450021 C1450019 C1450017 C1450020 C1450022 C1450014 C1450016 C1450011 C1450018 C0079691 C1881373 C0728762 C0720313 C0721340 C1450012 C0733850 C0721346 |
|
| DC |
1 |
|
| definition |
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. |
|
| DX |
19650101 |
|
| FX |
D011988 D006981 |
|
| HN |
1965; use THYROXIN 1963-1964; for LEVOTHYROXINE use LEVOTHYROXINE 1991-2001, use THYROXINE 1966-1990 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
Q51BO43MG4 0 |
|
| Inverse of RO | ||
| LT |
TRD |
|
| Machine permutation |
1965; see THYROXIN 1963-1964; for LEVOTHYROXINE see LEVOTHYROXINE 1991-2001, see THYROXINE 1966-1990, see LEVOTHYROXINE 1963-1965 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C018539 http://purl.bioontology.org/ontology/MESH/C045736 http://purl.bioontology.org/ontology/MESH/C018591 http://purl.bioontology.org/ontology/MESH/C054785 http://purl.bioontology.org/ontology/MESH/C011126 http://purl.bioontology.org/ontology/MESH/C000626766 http://purl.bioontology.org/ontology/MESH/C010150 http://purl.bioontology.org/ontology/MESH/C035912 http://purl.bioontology.org/ontology/MESH/C010516 |
|
| MDA |
19990101 |
|
| MMR |
20180228 |
|
| MN |
D06.472.931.812 D12.125.072.050.767 |
|
| notation |
D013974 |
|
| prefLabel |
Thyroxine |
|
| RR |
51-48-9 7488-70-2 (Thyroxine) |
|
| TERMUI |
T048349 T580509 T040987 T040984 T040986 T048352 T580452 T580485 T580468 T580467 T048350 T040985 T580478 T048348 T580470 T580472 T040988 T580506 T580454 T048347 T048346 T580497 T580480 T580511 T048353 T436487 T580475 T580458 T048351 T580493 T580513 T580491 T580482 T580504 T580456 T048354 T580462 T048345 T580495 T100176 |
|
| TH |
NLM (1996) US NLM (1965) NLM (2002) MX UK NL NLM (1991) NLM (2005) CA FDA SRS (2014) ES UNK (19XX) DE AU FR IE |
|
| tui |
T125 T109 T116 T121 |
|
| subClassOf |