Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Phenytoin
Synonyms

Sodium Diphenylhydantoinate

Diphenylhydantoin

Dihydan

5,5-diphenylimidazolidine-2,4-dione

Epanutin

Antisacer

Dilantin

5,5-Diphenylhydantoin

Epamin

Hydantol

Phenytoin Sodium

2,4-Imidazolidinedione, 5,5-diphenyl-

Fenitoin

Phenhydan

Diphenylhydantoinate, Sodium

Difenin

Definitions

An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.

ID

http://purl.bioontology.org/ontology/MESH/D010672

altLabel

Sodium Diphenylhydantoinate

Diphenylhydantoin

Dihydan

5,5-diphenylimidazolidine-2,4-dione

Epanutin

Antisacer

Dilantin

5,5-Diphenylhydantoin

Epamin

Hydantol

Phenytoin Sodium

2,4-Imidazolidinedione, 5,5-diphenyl-

Fenitoin

Phenhydan

Diphenylhydantoinate, Sodium

Difenin

AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C0699512

C0699513

C0699514

C5545310

C0700656

C0699511

C0031507

C0600299

C0237417

C0700657

DC

1

definition

An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.

DX

19660101

HN

78; was DIPHENYLHYDANTOIN 1963-77

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of RB

4182431BJH

6158TKW0C5

0

isa

http://purl.bioontology.org/ontology/MESH/D065694

http://purl.bioontology.org/ontology/MESH/D000927

http://purl.bioontology.org/ontology/MESH/D061567

LT

TRD

Machine permutation

78; was DIPHENYLHYDANTOIN 1963-77

Mapped from

http://purl.bioontology.org/ontology/MESH/C072638

http://purl.bioontology.org/ontology/MESH/C046868

http://purl.bioontology.org/ontology/MESH/C022301

http://purl.bioontology.org/ontology/MESH/C033362

http://purl.bioontology.org/ontology/MESH/C552285

http://purl.bioontology.org/ontology/MESH/C058470

http://purl.bioontology.org/ontology/MESH/C021193

http://purl.bioontology.org/ontology/MESH/C011064

http://purl.bioontology.org/ontology/MESH/C427543

http://purl.bioontology.org/ontology/MESH/C003109

http://purl.bioontology.org/ontology/MESH/C106138

http://purl.bioontology.org/ontology/MESH/C024222

http://purl.bioontology.org/ontology/MESH/C012438

http://purl.bioontology.org/ontology/MESH/C104023

http://purl.bioontology.org/ontology/MESH/C053062

http://purl.bioontology.org/ontology/MESH/C030590

http://purl.bioontology.org/ontology/MESH/C116426

http://purl.bioontology.org/ontology/MESH/C041562

http://purl.bioontology.org/ontology/MESH/C012785

http://purl.bioontology.org/ontology/MESH/C085386

http://purl.bioontology.org/ontology/MESH/C085385

http://purl.bioontology.org/ontology/MESH/C027364

http://purl.bioontology.org/ontology/MESH/C027363

http://purl.bioontology.org/ontology/MESH/C092335

http://purl.bioontology.org/ontology/MESH/C057787

http://purl.bioontology.org/ontology/MESH/C118245

http://purl.bioontology.org/ontology/MESH/C034408

http://purl.bioontology.org/ontology/MESH/C043115

http://purl.bioontology.org/ontology/MESH/C043114

http://purl.bioontology.org/ontology/MESH/C043113

http://purl.bioontology.org/ontology/MESH/C013971

http://purl.bioontology.org/ontology/MESH/C073336

http://purl.bioontology.org/ontology/MESH/C088510

http://purl.bioontology.org/ontology/MESH/C088511

http://purl.bioontology.org/ontology/MESH/C038540

http://purl.bioontology.org/ontology/MESH/C001419

http://purl.bioontology.org/ontology/MESH/C043104

http://purl.bioontology.org/ontology/MESH/C073199

MDA

19990101

MMR

20210701

MN

D03.383.129.308.432.555.730

notation

D010672

OL

use PHENYTOIN to search DIPHENYLHYDANTOIN 1966-77

PA

D065694

D000927

D061567

prefLabel

Phenytoin

RR

4182431BJH

57-41-0 (Phenytoin)

TERMUI

T031541

T031536

T856539

T031539

T001105924

T000912684

T031538

T031537

T031533

T031534

T031535

T031540

T031544

T031543

T031542

TH

NLM (2015)

FDA SRS (2014)

UNK (19XX)

NLM (2022)

INN (19XX)

NLM (2017)

USAN (1975)

USP (19XX)

BAN (19XX)

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D006827

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/RXNORM/202740 RXNORM CUI
http://purl.bioontology.org/ontology/RCD/x02bQ RCD CUI
http://purl.bioontology.org/ontology/MSHFRE/D010672 MSHFRE CUI
http://purl.bioontology.org/ontology/MSHFRE/D010672 MSHFRE CUI
http://purl.bioontology.org/ontology/CSP/1548-7299 CRISP CUI
http://purl.bioontology.org/ontology/SCTSPA/387220006 SCTSPA CUI
http://purl.bioontology.org/ontology/SCTSPA/40556005 SCTSPA CUI
http://purl.bioontology.org/ontology/VANDF/4017856 VANDF CUI
http://purl.bioontology.org/ontology/SNOMEDCT/40556005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/NDDF/001617 NDDF CUI
http://purl.bioontology.org/ontology/RCD/dn8.. RCD CUI
http://purl.bioontology.org/ontology/SNMI/C-61640 SNMI CUI
http://purl.bioontology.org/ontology/CSP/1548-7299 CRISP CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387220006 SNOMEDCT CUI
http://purl.bioontology.org/ontology/LNC/LP14732-9 LOINC CUI
http://purl.bioontology.org/ontology/RXNORM/8183 RXNORM CUI
http://purl.bioontology.org/ontology/RCD/X796l RCD CUI
http://purl.bioontology.org/ontology/LNC/MTHU002993 LOINC CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146211 NDFRT CUI
http://purl.bioontology.org/ontology/ATC/N03AB02 ATC CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006023 NDFRT CUI
http://purl.bioontology.org/ontology/SCTSPA/387416005 SCTSPA CUI
http://purl.bioontology.org/ontology/NDDF/001619 NDDF CUI
http://purl.bioontology.org/ontology/VANDF/4017857 VANDF CUI
http://purl.bioontology.org/ontology/SNMI/C-61641 SNMI CUI
http://purl.bioontology.org/ontology/RXNORM/71227 RXNORM CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146212 NDFRT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387416005 SNOMEDCT CUI
http://www.drugbank.ca/drugs/DB00252 FTC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9622 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 DOID LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 HHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_8107 OBA LOOM
http://purl.obolibrary.org/obo/NCIT_C741 BERO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C741 NCIT LOOM
http://scai.fraunhofer.de/MSOntology#phenytoin MSO LOOM
http://purl.bioontology.org/ontology/VANDF/4017856 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010672 RH-MESH LOOM
http://www.case.edu/EpSO.owl#Phenytoin MEPO LOOM
http://www.semanticweb.org/dellvostro3750/ontologies/2018/2/untitled-ontology-10#phenytoin HP_O LOOM
http://stirdf.jst.go.jp/id/200907036802684511 IOBC LOOM
http://www.case.edu/EpilepsyOntology.owl#Phenytoin EPSO LOOM
http://bmi.utah.edu/ontologies/hfontology/C0031507 HFO LOOM
http://purl.bioontology.org/ontology/SNMI/C-61640 SNMI LOOM
http://www.semanticweb.org/ftuha/ontologies/2021/5/FRMO-01untitled-ontology-175/Phenytoin FRMO LOOM
http://purl.obolibrary.org/obo/OMIT_0011660 OMIT LOOM
http://www.co-ode.org/ontologies/galen#Phenytoin GALEN LOOM
http://purl.bioontology.org/ontology/CSP/1548-7299 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.308.432.555.730 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387220006 SNOMEDCT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018190 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/LNC/LP14732-9 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/8183 RXNORM LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146211 ODAE LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146211 OCVDAE LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0031507 OCHV LOOM
http://purl.obolibrary.org/obo/MESH_D010672 BERO LOOM
http://purl.jp/bio/4/id/200906028151591025 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002993 LOINC LOOM
http://scai.fraunhofer.de/MSOntology#Phenytoin MSO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146211 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/N03AB02 ATC LOOM
https://go.drugbank.com/drugs/DB00252 MDM LOOM
rgo:30745 GAMUTS LOOM
http://purl.bioontology.org/ontology/CPT/1011174 CPT LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Phenytoin STMSO LOOM