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Last uploaded: August 28, 2024

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Preferred Name	Melphalan
Synonyms	L-PAM Sarkolysin Merphalan Sarcolysine 4-(Bis(2-chloroethyl)amino)phenylalanine Mustard, Phenylalanine Alkeran L-Phenylalanine, 4-(bis(2-chloroethyl)amino)- Medphalan Phenylalanine Mustard
Definitions	An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.
ID	http://purl.bioontology.org/ontology/MESH/D008558
altLabel	L-PAM Sarkolysin Merphalan Sarcolysine 4-(Bis(2-chloroethyl)amino)phenylalanine Mustard, Phenylalanine Alkeran L-Phenylalanine, 4-(bis(2-chloroethyl)amino)- Medphalan Phenylalanine Mustard
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0025444 C0591063 C0025144 C0025241 C5441592
DC	1
definition	An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.
DX	19660101
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	Q41OR9510P 0
isa	http://purl.bioontology.org/ontology/MESH/D018906 http://purl.bioontology.org/ontology/MESH/D019653
LT	TRD
Machine permutation	PEPTICHEMIO was see under NITROGEN MUSTARD COMPOUNDS 1975-80
Mapped from	http://purl.bioontology.org/ontology/MESH/C040240 http://purl.bioontology.org/ontology/MESH/C014719 http://purl.bioontology.org/ontology/MESH/C089190 http://purl.bioontology.org/ontology/MESH/C034854 http://purl.bioontology.org/ontology/MESH/C015691 http://purl.bioontology.org/ontology/MESH/C000654 http://purl.bioontology.org/ontology/MESH/C507380 http://purl.bioontology.org/ontology/MESH/C096752 http://purl.bioontology.org/ontology/MESH/C041701 http://purl.bioontology.org/ontology/MESH/C061958 http://purl.bioontology.org/ontology/MESH/C008148 http://purl.bioontology.org/ontology/MESH/C407425 http://purl.bioontology.org/ontology/MESH/C057058 http://purl.bioontology.org/ontology/MESH/C042307 http://purl.bioontology.org/ontology/MESH/C088031 http://purl.bioontology.org/ontology/MESH/C055592 http://purl.bioontology.org/ontology/MESH/C040287 http://purl.bioontology.org/ontology/MESH/C027126 http://purl.bioontology.org/ontology/MESH/C073284 http://purl.bioontology.org/ontology/MESH/C056620 http://purl.bioontology.org/ontology/MESH/C060410 http://purl.bioontology.org/ontology/MESH/C412623 http://purl.bioontology.org/ontology/MESH/C112055 http://purl.bioontology.org/ontology/MESH/C048677 http://purl.bioontology.org/ontology/MESH/C101309 http://purl.bioontology.org/ontology/MESH/C061971 http://purl.bioontology.org/ontology/MESH/C023978 http://purl.bioontology.org/ontology/MESH/C059288 http://purl.bioontology.org/ontology/MESH/C065216 http://purl.bioontology.org/ontology/MESH/C090161 http://purl.bioontology.org/ontology/MESH/C524336 http://purl.bioontology.org/ontology/MESH/C078474 http://purl.bioontology.org/ontology/MESH/C104874 http://purl.bioontology.org/ontology/MESH/C526265 http://purl.bioontology.org/ontology/MESH/C014803 http://purl.bioontology.org/ontology/MESH/C045927 http://purl.bioontology.org/ontology/MESH/C078008 http://purl.bioontology.org/ontology/MESH/C063562 http://purl.bioontology.org/ontology/MESH/C058954 http://purl.bioontology.org/ontology/MESH/C475940 http://purl.bioontology.org/ontology/MESH/C043998 http://purl.bioontology.org/ontology/MESH/C417973 http://purl.bioontology.org/ontology/MESH/C030227 http://purl.bioontology.org/ontology/MESH/C047804 http://purl.bioontology.org/ontology/MESH/C086095 http://purl.bioontology.org/ontology/MESH/C081716 http://purl.bioontology.org/ontology/MESH/C051713 http://purl.bioontology.org/ontology/MESH/C037052 http://purl.bioontology.org/ontology/MESH/C051105 http://purl.bioontology.org/ontology/MESH/C047871 http://purl.bioontology.org/ontology/MESH/C064400 http://purl.bioontology.org/ontology/MESH/C038967 http://purl.bioontology.org/ontology/MESH/C039176 http://purl.bioontology.org/ontology/MESH/C052557 http://purl.bioontology.org/ontology/MESH/C072921 http://purl.bioontology.org/ontology/MESH/C047771 http://purl.bioontology.org/ontology/MESH/C039848 http://purl.bioontology.org/ontology/MESH/C053596 http://purl.bioontology.org/ontology/MESH/C085528 http://purl.bioontology.org/ontology/MESH/C044428 http://purl.bioontology.org/ontology/MESH/C585069 http://purl.bioontology.org/ontology/MESH/C076572 http://purl.bioontology.org/ontology/MESH/C052608 http://purl.bioontology.org/ontology/MESH/C405767 http://purl.bioontology.org/ontology/MESH/C434884 http://purl.bioontology.org/ontology/MESH/C406271 http://purl.bioontology.org/ontology/MESH/C034584 http://purl.bioontology.org/ontology/MESH/C064398 http://purl.bioontology.org/ontology/MESH/C041860 http://purl.bioontology.org/ontology/MESH/C512869 http://purl.bioontology.org/ontology/MESH/C106279
MDA	19990101
MMR	20130708
MN	D12.125.072.050.685.500 D02.455.526.728.650.594
notation	D008558
PA	D018906 D019653
prefLabel	Melphalan
RR	148-82-3 (Melphalan)
TERMUI	T025463 T025461 T025467 T025468 T025462 T025466 T025465 T025464 T025469
TH	FDA SRS (2014) UNK (19XX) USAN (1963) INN (19XX) USP (19XX) BAN (19XX)
tui	T116 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D009588 http://purl.bioontology.org/ontology/MESH/D010649

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/0124-3600	CRISP	CUI
http://purl.bioontology.org/ontology/RXNORM/151325	RXNORM	CUI
http://purl.bioontology.org/ontology/SCTSPA/544002	SCTSPA	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000779085	PDQ	CUI
http://purl.bioontology.org/ontology/MSHFRE/D008558	MSHFRE	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000779085	PDQ	CUI
http://purl.bioontology.org/ontology/RCD/x02TG	RCD	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007351	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387297002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/RXNORM/6718	RXNORM	CUI
http://purl.bioontology.org/ontology/RCD/h19..	RCD	CUI
http://purl.bioontology.org/ontology/SNMI/C-78150	SNMI	CUI
http://purl.bioontology.org/ontology/ATC/L01AA03	ATC	CUI
http://purl.bioontology.org/ontology/CSP/1371-9348	CRISP	CUI
http://purl.bioontology.org/ontology/NDDF/002633	NDDF	CUI
http://purl.bioontology.org/ontology/CSP/0124-3600	CRISP	CUI
http://purl.bioontology.org/ontology/VANDF/4018763	VANDF	CUI
http://purl.bioontology.org/ontology/SCTSPA/387297002	SCTSPA	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000779085	PDQ	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/544002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147066	NDFRT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D008558	MSHFRE	CUI
http://purl.obolibrary.org/obo/CHEBI_28876	DOID	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	OBA	LOOM
http://purl.jp/bio/4/id/200906039168637381	IOBC	LOOM
http://purl.bioontology.org/ontology/npo#NPO_874	NPO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025241	OCHV	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387297002	SNOMEDCT	LOOM
http://purl.obolibrary.org/obo/NCIT_C633	BERO	LOOM
http://stirdf.jst.go.jp/id/200907075807738950	IOBC	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017033	PMAPP-PMO	LOOM
http://www.co-ode.org/ontologies/galen#Melphalan	GALEN	LOOM
http://purl.bioontology.org/ontology/RXNORM/6718	RXNORM	LOOM
http://purl.bioontology.org/ontology/RCD/h19..	RCD	LOOM
http://purl.bioontology.org/ontology/SNMI/C-78150	SNMI	LOOM
http://purl.bioontology.org/ontology/ATC/L01AA03	ATC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.125.072.050.685.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/NDDF/002633	NDDF	LOOM
rgo:15183	GAMUTS	LOOM
http://purl.bioontology.org/ontology/CSP/0124-3600	CRISP	LOOM
https://go.drugbank.com/drugs/DB01042	MDM	LOOM
http://purl.bioontology.org/ontology/VANDF/4018763	VANDF	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008558	RH-MESH	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000779085	PDQ	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.526.728.650.594	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0009624	OMIT	LOOM
http://purl.obolibrary.org/obo/MESH_D008558	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	CCONT	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	DOID	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	FB-CV	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	HHEAR	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_28876	PECO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7908	OCHV	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147066	NDFRT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C633	NCIT	LOOM