Human Reference Atlas

Last uploaded: June 14, 2024
Preferred Name

Endocrine pancreas
Synonyms

endocrine part of pancreas

islets of Langerhans part of pancreas

pars endocrina pancreatis

endocrine pancreas

Definitions

The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin.

ID

http://purl.obolibrary.org/obo/UBERON_0000016

altLabel

endocrine part of pancreas

islets of Langerhans part of pancreas

pars endocrina pancreatis

endocrine pancreas

ccf_is_provisional

false

ccf_part_of

http://purl.obolibrary.org/obo/UBERON_0001978

ccf_pref_label

Endocrine pancreas

definition

The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin.

editor note

create a separate class for distributed pancreas, eg cyclostomes?

external_definition

The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO]

The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG]

has exact synonym

pars endocrina pancreatis

endocrine pancreas

has related synonym

endocrine part of pancreas

islets of Langerhans part of pancreas

has_obo_namespace

uberon

homology_notes

In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]

id

UBERON:0000016

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

http://purl.obolibrary.org/obo/uberon/core#efo_slim

http://purl.obolibrary.org/obo/uberon/core#organ_slim

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

isDefinedBy

http://purl.obolibrary.org/obo/uberon.owl

label

endocrine pancreas

notation

UBERON:0000016

part_of

http://purl.obolibrary.org/obo/UBERON_0001264

http://purl.obolibrary.org/obo/UBERON_0000949

http://purl.obolibrary.org/obo/NCBITaxon_6072

prefLabel

Endocrine pancreas

present in taxon

http://purl.obolibrary.org/obo/NCBITaxon_9606

taxon_notes

endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys

treeView

http://purl.obolibrary.org/obo/UBERON_0001264

http://purl.obolibrary.org/obo/UBERON_0000949

http://purl.obolibrary.org/obo/NCBITaxon_6072

xRef

NCIT:C32509

VHOG:0000049

EMAPA:35305

MA:0001582

BTO:0000650

Wikipedia:Islets_of_Langerhans

SCTID:361339003

TAO:0001260

EFO:0002542

MESH:D007515

ZFA:0001260

FMA:16018

EV:0100129

CALOHA:TS-1302

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000471

http://purl.obolibrary.org/obo/UBERON_0004119

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Delete Mapping To Ontology Source
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