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Hearing Impairment Ontology
Last uploaded:
October 31, 2019
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| Preferred Name | Insulin | |
| Synonyms |
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| Definitions |
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (glycogenolysis; gluconeogenesis) and indirectly by suppressing glucagon secretion and lipolysis. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (diabetes mellitus, type 1). |
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| ID |
http://purl.obolibrary.org/obo/HIO_0000186 |
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| description |
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (glycogenolysis; gluconeogenesis) and indirectly by suppressing glucagon secretion and lipolysis. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (diabetes mellitus, type 1).
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| created_by |
Jade Hotchkiss
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| creation_date |
2019-06-10T19:50:47.249828Z
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| database cross reference |
MESH:D007328
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| definition source | ||
| existence in other ontologies |
Sufficient
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| hasExactSynonym |
Sodium Insulin
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| label |
Insulin
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| prefixIRI |
HIO:0000186
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| prefLabel |
Insulin
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| subClassOf |
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