loading...| Preferred Name | AKT phosphorylates targets in the cytosol | |
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| Definitions |
Edited: Jassal, B, 2011-05-11 Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 Following activation, AKT can phosphorylate an array of target proteins in the cytoplasm, many of which are involved in cell survival control. Phosphorylation of TSC2 feeds positively to the TOR kinase, which, in turn, contributes to AKT activation (positive feedback loop). |
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| ID |
http://purl.obolibrary.org/obo/HINO_0016077 |
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| comment |
Edited: Jassal, B, 2011-05-11 Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 Following activation, AKT can phosphorylate an array of target proteins in the cytoplasm, many of which are involved in cell survival control. Phosphorylation of TSC2 feeds positively to the TOR kinase, which, in turn, contributes to AKT activation (positive feedback loop). |
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| definition source |
Reactome, http://www.reactome.org |
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| label |
AKT phosphorylates targets in the cytosol |
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| prefixIRI |
HINO:0016077 |
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| prefLabel |
AKT phosphorylates targets in the cytosol |
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| seeAlso |
Reactome Database ID Release 43198323 ReactomeREACT_12564 |
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| has_part |
http://purl.obolibrary.org/obo/HINO_0009541 http://purl.obolibrary.org/obo/HINO_0009556 http://purl.obolibrary.org/obo/HINO_0009559 http://purl.obolibrary.org/obo/HINO_0009554 http://purl.obolibrary.org/obo/HINO_0009558 http://purl.obolibrary.org/obo/HINO_0009557 |