Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

AKT phosphorylates p21Cip1 and p27Kip1
Synonyms
Definitions

Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 Phosphorylation of p27Kip1 at T157 and of p21Cip1 at T145 by AKT leads to their retention in the cytoplasm, segregating these cyclin-dependent kinase (CDK) inhibitors from cyclin-CDK complexes.

ID

http://purl.obolibrary.org/obo/HINO_0009558

comment

Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07

Reviewed: Greene, LA, 2007-11-08 15:39:37

Phosphorylation of p27Kip1 at T157 and of p21Cip1 at T145 by AKT leads to their retention in the cytoplasm, segregating these cyclin-dependent kinase (CDK) inhibitors from cyclin-CDK complexes.

definition source

Reactome, http://www.reactome.org

Pubmed12244303

has input

http://purl.obolibrary.org/obo/HINO_0024932

http://purl.obolibrary.org/obo/CHEBI_15422

has output

http://purl.obolibrary.org/obo/HINO_0024931

http://purl.obolibrary.org/obo/CHEBI_16761

label

AKT phosphorylates p21Cip1 and p27Kip1

prefixIRI

HINO:0009558

prefLabel

AKT phosphorylates p21Cip1 and p27Kip1

seeAlso

EC Number: 2.7.11

Reactome Database ID Release 43198613

ReactomeREACT_12420

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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