loading...| Preferred Name | macrophage | |
| Synonyms |
histiocyte |
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| Definitions |
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. |
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| ID |
http://purl.obolibrary.org/obo/CL_0000235 |
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| comment |
Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. |
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| database_cross_reference |
FMA:83585 FMA:63261 BTO:0000801 CALOHA:TS-0587 |
|
| definition |
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
|
| has_exact_synonym |
histiocyte |
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| has_obo_namespace |
cell |
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| imported from | ||
| label |
macrophage |
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| prefixIRI |
CL:0000235 |
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| prefLabel |
macrophage |
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| subClassOf |