loading...| Preferred Name |
macrophage |
|
| Synonyms |
histiocyte |
|
| Definitions |
Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
|
| ID |
http://purl.obolibrary.org/obo/CL_0000235 |
|
| comment |
Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. |
|
| database_cross_reference |
FMA:83585 FMA:63261 BTO:0000801 CALOHA:TS-0587 |
|
| definition |
A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
|
| has_exact_synonym |
histiocyte |
|
| has_obo_namespace |
cell |
|
| imported from | ||
| label |
macrophage |
|
| prefixIRI |
CL:0000235 |
|
| prefLabel |
macrophage |
|
| subClassOf |