loading...| Preferred Name | hemophagocytic lymphohistiocytosis | |
| Synonyms |
haemophagocytic syndrome |
|
| Definitions |
A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. Xref MGI. MESH:C537250 added from NeuroDevNet [WAK]. |
|
| ID |
http://purl.obolibrary.org/obo/DOID_0050120 |
|
| comment |
Xref MGI. MESH:C537250 added from NeuroDevNet [WAK]. |
|
| alternative label |
haemophagocytic syndrome |
|
| database_cross_reference |
MESH:D051359 SNOMEDCT_US_2023_03_01:190958003 ICD10CM:D76.1 UMLS_CUI:C0024291 MIM:PS267700 GARD:6589 NCI:C34792 ORDO:540 |
|
| definition |
A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. Xref MGI. MESH:C537250 added from NeuroDevNet [WAK]. |
|
| has exact synonym |
haemophagocytic syndrome |
|
| has symptom |
http://purl.obolibrary.org/obo/SYMP_0019142 |
|
| has_alternative_id |
DOID:6453 |
|
| has_obo_namespace |
disease_ontology |
|
| id |
DOID:0050120 |
|
| in_subset | ||
| label |
hemophagocytic lymphohistiocytosis |
|
| notation |
DOID:0050120 |
|
| note |
A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. Xref MGI. MESH:C537250 added from NeuroDevNet [WAK]. |
|
| preferred label |
hemophagocytic lymphohistiocytosis |
|
| prefLabel |
hemophagocytic lymphohistiocytosis |
|
| subClassOf |