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FlyBase Controlled Vocabulary
Last uploaded:
December 5, 2024
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| Preferred Name | busulfan | |
| Synonyms |
1,4-Dimesyloxybutane Tetramethylene bis(methanesulfonate) 1,4-Dimethanesulfonoxybutane 1,4-Bis(methanesulfonoxy)butane 1,4-Butanediol dimethanesulfonate Busulfan |
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| Definitions |
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_28901 |
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| database_cross_reference |
KEGG:C06862 KEGG:D00248 DrugBank:DB01008 LINCS:LSM-5388 Patent:US2917432 Wikipedia:Busulfan
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|
| definition |
A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant.
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| has role |
http://purl.obolibrary.org/obo/CHEBI_50905 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_67105 |
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| has_alternative_id |
CHEBI:18936 CHEBI:3225
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| has_exact_synonym |
Busulfan
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| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
1,4-Dimesyloxybutane Tetramethylene bis(methanesulfonate) 1,4-Dimethanesulfonoxybutane 1,4-Bis(methanesulfonoxy)butane 1,4-Butanediol dimethanesulfonate
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|
| id |
CHEBI:28901
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| in_subset | ||
| label |
busulfan
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|
| notation |
CHEBI:28901
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| prefLabel |
busulfan
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| subClassOf |
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