loading...| Preferred Name |
leukemia |
|
| Synonyms |
leukaemia (disease) leukemia, disease leukemia, malignant leukemias, general leukemia (disease) blood (leukemia) leukemia leukemias leukaemia NOS |
|
| Definitions |
A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0000565 |
|
| closeMatch |
http://identifiers.org/snomedct/188762002 http://identifiers.org/snomedct/190029004 http://identifiers.org/snomedct/154598008 http://identifiers.org/snomedct/190071003 http://identifiers.org/snomedct/87163000 http://identifiers.org/snomedct/255049003 http://identifiers.org/snomedct/190024009 |
|
| database_cross_reference |
ICD9:207.80 ICD9:208.90 ICD10:C95.9 EFO:0000565 NANDO:2100002 SCTID:93143009 ICDO:9800/3 UMLS:C0023418 ICD10:C95.90 ICD9:208.80 MESH:D007938 DOID:1240 HP:0001909 ICD10:C95 ICD9:207 ICD9:207.8 ICD9:208 ICD9:208.8 ICD9:208.9 NCIT:C3161 MONDO:0005059 |
|
| definition |
A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years. |
|
| exactMatch |
http://identifiers.org/mesh/D007938 http://identifiers.org/snomedct/93143009 http://purl.obolibrary.org/obo/NCIT_C3161 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
leukaemia (disease) leukemia, disease leukemia, malignant leukemias, general leukemia (disease) blood (leukemia) leukemia leukemias |
|
| has_related_synonym |
leukaemia NOS |
|
| IAO_0000589 |
leukemia (disease) |
|
| id |
EFO:0000565 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare |
|
| label |
leukemia |
|
| notation |
EFO:0000565 |
|
| prefLabel |
leukemia |
|
| subClassOf | ||
| excluded_subClassOf |