Preferred Name

optic vesicle
Synonyms

eye vesicle

optic vesicles

ocular vesicle

evagination

Definitions

The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. Genes: Six3, Pax6, Rx1 are expressed together in the tip of the neural plate [ISBN:9780878932504 "Developmental Biology"]. Development notes: During subsequent develop- ment, the optic vesicle invaginates and becomes a two-layered structure with an inner neural retina and outer retinal pigment epithelium. As soon as the developing optic vesicle makes contact with the overlying ectoderm, it induces the ectoderm to thicken and form the lens placode [PMID:16496288]

ID

http://purl.obolibrary.org/obo/UBERON_0004128

comment

Genes: Six3, Pax6, Rx1 are expressed together in the tip of the neural plate [ISBN:9780878932504 "Developmental Biology"]. Development notes: During subsequent develop- ment, the optic vesicle invaginates and becomes a two-layered structure with an inner neural retina and outer retinal pigment epithelium. As soon as the developing optic vesicle makes contact with the overlying ectoderm, it induces the ectoderm to thicken and form the lens placode [PMID:16496288]

database_cross_reference

NCIT:C34236

EHDAA2:0001320

SCTID:362864008

VHOG:0000165

UMLS:C0231106

EMAPA:16540

Wikipedia:Optic_vesicles

ZFA:0000050

XAO:0000228

TAO:0000050

AAO:0011039

FMA:293357

definition

The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA].

depiction

http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png

developmentally induced by

http://purl.obolibrary.org/obo/UBERON_0004880

develops_from

http://purl.obolibrary.org/obo/UBERON_0003071

http://purl.obolibrary.org/obo/UBERON_0002346

hasOBONamespace

uberon

hasRelatedSynonym

eye vesicle

optic vesicles

ocular vesicle

evagination

id

UBERON:0004128

inSubset

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#pheno_slim

label

optic vesicle

notation

UBERON:0004128

part_of

http://purl.obolibrary.org/obo/UBERON_0010312

prefLabel

optic vesicle

treeView

http://purl.obolibrary.org/obo/UBERON_0003071

http://purl.obolibrary.org/obo/UBERON_0002346

http://purl.obolibrary.org/obo/UBERON_0010312

UBPROP_0000003

(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles.[well established][VHOG]

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000479

http://purl.obolibrary.org/obo/UBERON_0004121

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Delete Mapping To Ontology Source
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