Drug Target Ontology

Last uploaded: February 15, 2018
Preferred Name

hypothalamus
Synonyms
Definitions

The ventral part of the diencephalon that forms the floor and part of the lateral wall of the third ventricle. Anatomically, it includes the preoptic area, optic tract, optic chiasm, mammillary bodies, tuber cinereum, infundibulum, and neurohypophysis, but for physiological purposes the neurohypophysis is considered a distinct structure. The hypothalamus may be divided into five regions or areas (area hypothalamica rostralis, area hypothalamica dorsalis, area hypothalamica intermedia, area hypothalamica lateralis and area hypothalamica posterior) or into three longitudinal zones (periventricular zone, medial zone, and lateral zone). The hypothalamic nuclei constitute that part of the corticodiencephalic mechanism that activates, controls and integrates the peripheral autonomic mechanisms, endocrine activity, and many somatic functions, e.g., a general regulation of water balance, body temperature, sleep, and food intake, and the development of secondary sex characteristics. The hypothalamus secretes vasopressin and oxytocin, which are stored in the pituitary, as well as many releasing factors (hypophysiotropic hormones), by means of which it exerts control over functions of the adenohypophysis.

ID

http://purl.obolibrary.org/obo/BTO_0000614

definition

The ventral part of the diencephalon that forms the floor and part of the lateral wall of the third ventricle. Anatomically, it includes the preoptic area, optic tract, optic chiasm, mammillary bodies, tuber cinereum, infundibulum, and neurohypophysis, but for physiological purposes the neurohypophysis is considered a distinct structure. The hypothalamus may be divided into five regions or areas (area hypothalamica rostralis, area hypothalamica dorsalis, area hypothalamica intermedia, area hypothalamica lateralis and area hypothalamica posterior) or into three longitudinal zones (periventricular zone, medial zone, and lateral zone). The hypothalamic nuclei constitute that part of the corticodiencephalic mechanism that activates, controls and integrates the peripheral autonomic mechanisms, endocrine activity, and many somatic functions, e.g., a general regulation of water balance, body temperature, sleep, and food intake, and the development of secondary sex characteristics. The hypothalamus secretes vasopressin and oxytocin, which are stored in the pituitary, as well as many releasing factors (hypophysiotropic hormones), by means of which it exerts control over functions of the adenohypophysis.

hasOBONamespace

BrendaTissueOBO

id

BTO:0000614

imported from

http://purl.obolibrary.org/obo/bto.owl

label

hypothalamus

prefixIRI

BTO:0000614

prefLabel

hypothalamus

subClassOf

http://www.drugtargetontology.org/dto/DTO_00000018

http://purl.obolibrary.org/obo/BTO_0001488

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http://purl.obolibrary.org/obo/BTO_0000614 BTO SAME_URI
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http://purl.obolibrary.org/obo/TAO_0000032 TAO LOOM
http://purl.jp/bio/4/id/200906001712588597 IOBC LOOM
http://mouse.brain-map.org/atlas/index.html#HY ABA-AMB LOOM
http://purl.obolibrary.org/obo/EHDA_6557 EHDA LOOM
http://bioontology.org/projects/ontologies/birnlex#birnlex_734 BIRNLEX LOOM
http://purl.obolibrary.org/obo/EMAPA_17536 EMAPA LOOM
http://purl.obolibrary.org/obo/OMIT_0008164 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A08.186.211.464.482 RH-MESH LOOM
http://purl.obolibrary.org/obo/XAO_0004070 XPO LOOM
http://purl.obolibrary.org/obo/XAO_0004070 XAO LOOM
http://localhost/plosthes.2017-1#9234 PLOSTHES LOOM
http://www.co-ode.org/ontologies/galen#Hypothalamus GALEN LOOM
urn:absolute:RadiationOncologyStructuresOntology#Hypothalamus ROS LOOM
http://doe-generated-ontology.com/OntoPneumo#Hypothalamus ONTOPNEUMO LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 NPOKB LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 CL LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 UBERON LOOM
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http://purl.obolibrary.org/obo/UBERON_0001898 OBI_BCGO LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 EFO LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 DOID LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 ENVO LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 PCL LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 EPIO LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 GO-PLUS LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 EFO LOOM
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http://purl.obolibrary.org/obo/UBERON_0001898 DDSS LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 HRA LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 NIFSTD LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 MAXO LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 FNS-H LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 NMDCO LOOM
http://purl.obolibrary.org/obo/UBERON_0001898 OBA LOOM
http://purl.obolibrary.org/obo/VHOG_0000179 VHOG LOOM
http://purl.bioontology.org/ontology/CSP/0478-2089 CRISP LOOM
http://www.projecthalo.com/aura#Hypothalamus AURA LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0020663 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A08.186.211.730.317.357 RH-MESH LOOM
http://purl.org/obo/owlapi/fma#FMA_62008 BIOMODELS LOOM
http://purl.obolibrary.org/obo/EHDAA_5446 EHDAA LOOM
http://purl.bioontology.org/ontology/RCD/XC0aI RCD LOOM
http://purl.obolibrary.org/obo/EHDA_8774 EHDA LOOM
http://purl.obolibrary.org/obo/ZFA_0000032 ZFA LOOM
http://purl.obolibrary.org/obo/ZFA_0000032 ZP LOOM
http://www.semanticweb.org/rjyy/ontologies/2015/5/ESSO#Hypothalamus ESSO LOOM
http://www.semanticweb.org/rjyy/ontologies/2015/5/ESSO#Hypothalamus MEPO LOOM
http://purl.obolibrary.org/obo/EHDAA2_0000802 EHDAA2 LOOM
http://purl.obolibrary.org/obo/EHDA_5447 EHDA LOOM
http://purl.obolibrary.org/obo/MAT_0000112 MAT LOOM
http://radlex.org/RID/RID6639 RADLEX LOOM
http://neuromorpho.org/ontologies/vertebrateH.owl#NMOBr_194 NMOBR LOOM
http://purl.obolibrary.org/obo/BTO_0000614 BTO LOOM
http://cocomac.g-node.org/services/custom_sql_query.php?sql=SELECT%20*%20from%20BrainMaps_BrainSiteAcronyms%20where%20ID=1619 NIFSTD LOOM
http://cocomac.g-node.org/services/custom_sql_query.php?sql=SELECT%20*%20from%20BrainMaps_BrainSiteAcronyms%20where%20ID=1614 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007031 RH-MESH LOOM
http://uri.neuinfo.org/nif/nifstd/birnlex_734 NIFSTD LOOM
http://purl.org/sig/ont/fma/fma62008 FMA LOOM
http://purl.org/sig/ont/fma/fma62008 ROO LOOM
http://www.semanticweb.org/ontologies/2009/9/Ontology1255357986125.owl#Hypothalamus BRCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12458 NCIT LOOM
http://purl.obolibrary.org/obo/MA_0000173 MA LOOM
http://scai.fraunhofer.de/MSOntology#Hypothalamus MSO LOOM
http://purl.obolibrary.org/obo/EHDA_7544 EHDA LOOM
http://api.brain-map.org/api/v2/data/Structure/1097 NPOKB LOOM
http://api.brain-map.org/api/v2/data/Structure/1097 NIFSTD LOOM
http://purl.obolibrary.org/obo/EHDA_9955 EHDA LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Hypothalamus APANEUROCLUSTER LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Hypothalamus APAONTO LOOM
http://purl.bioontology.org/ontology/MESH/D007031 MESH LOOM
http://purl.obolibrary.org/obo/FMA_62008 NIO LOOM