Preferred Name

hepatic encephalopathy

Synonyms

portal-systemic encephalopathy

encephalopathy, hepatic

Hepatoencephalopathy

Definitions

Hepatic encephalopathy is a syndrome observed in some patients with cirrhosis. It is defined as a spectrum of neuropsychiatric abnormalities in patients with liver dysfunction, when other known brain disease has been excluded.Signs and symptomsmay be debilitating, and they can begin mildly and gradually, or occur suddenly and severely. They may includepersonality or moodchanges, intellectual impairment, abnormal movements,a depressed level of consciousness, and other symptoms.There are several theories regarding the exact cause, butdevelopment of the condition isprobablyat least partiallydue to the effect of substances that are toxic to nerve tissue (neurotoxic), which are typically present with liver damage and/or liver disease. Treatment depends upon the severity of mental status changes and upon the certainty of the diagnosis.

ID

http://purl.obolibrary.org/obo/MONDO_0001711

has_exact_synonym

portal-systemic encephalopathy

has_related_synonym

encephalopathy, hepatic

Hepatoencephalopathy

label

hepatic encephalopathy

prefixIRI

MONDO:0001711

prefLabel

hepatic encephalopathy

seeAlso

https://rarediseases.info.nih.gov/diseases/10452/hepatic-encephalopathy

textual definition

Hepatic encephalopathy is a syndrome observed in some patients with cirrhosis. It is defined as a spectrum of neuropsychiatric abnormalities in patients with liver dysfunction, when other known brain disease has been excluded.Signs and symptomsmay be debilitating, and they can begin mildly and gradually, or occur suddenly and severely. They may includepersonality or moodchanges, intellectual impairment, abnormal movements,a depressed level of consciousness, and other symptoms.There are several theories regarding the exact cause, butdevelopment of the condition isprobablyat least partiallydue to the effect of substances that are toxic to nerve tissue (neurotoxic), which are typically present with liver damage and/or liver disease. Treatment depends upon the severity of mental status changes and upon the certainty of the diagnosis.

subClassOf

http://purl.obolibrary.org/obo/MONDO_0005560

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