The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	folic acid
Synonyms	(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid C19H19N7O6
ID	http://purl.obolibrary.org/obo/dinto_DB00158
AHFScode	88:08.00
ATCCode	B03BB01
binds	http://purl.obolibrary.org/obo/dinto_3342 http://purl.obolibrary.org/obo/dinto_2122 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_0300 http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_3587 http://purl.obolibrary.org/obo/dinto_2113 http://purl.obolibrary.org/obo/dinto_0588 http://purl.obolibrary.org/obo/dinto_2666 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1810 http://purl.obolibrary.org/obo/dinto_1365
CASRN	59-30-3
DBBrand	apo-folic folbal foliamin folipac folsav dosfolat b activ folcidin folsan folvron incafolic folsaure folettes folacin folvite acifolic foldine folacid millafol folicet cytofol
DBSynonym	vitamin be pteroylmonoglutamic acid vitamin bc vitamin m folate vitamin b9 pteroyl-l-monoglutamic acid pteroyl-l-glutamic acid pteroylglutamic acid
Definition	A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. [PubChem]
has effect	http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000500
InChI	InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChIKey	InChIKey=OVBPIULPVIDEAO-LBPRGKRZSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_0300
is metabolised by	http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_3587 http://purl.obolibrary.org/obo/dinto_2113
is substrate of	http://purl.obolibrary.org/obo/dinto_0293 http://purl.obolibrary.org/obo/dinto_3587 http://purl.obolibrary.org/obo/dinto_2113 http://purl.obolibrary.org/obo/dinto_0588 http://purl.obolibrary.org/obo/dinto_2666 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1810 http://purl.obolibrary.org/obo/dinto_1365
is transported by	http://purl.obolibrary.org/obo/dinto_0588 http://purl.obolibrary.org/obo/dinto_2666 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1810 http://purl.obolibrary.org/obo/dinto_1365
label	folic acid
may interact with	http://purl.obolibrary.org/obo/CHEBI_102524 http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/dinto_DB00794 http://purl.obolibrary.org/obo/dinto_DB00306 http://purl.obolibrary.org/obo/CHEBI_4888 http://purl.obolibrary.org/obo/dinto_DB01355 http://purl.obolibrary.org/obo/CHEBI_102216 http://purl.obolibrary.org/obo/dinto_DB00532 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/dinto_DB00312 http://purl.obolibrary.org/obo/dinto_DB01354 http://purl.obolibrary.org/obo/dinto_DB00237 http://purl.obolibrary.org/obo/dinto_DB01352 http://purl.obolibrary.org/obo/CHEBI_6758 http://purl.obolibrary.org/obo/dinto_DB01351 http://purl.obolibrary.org/obo/dinto_DB01320 http://purl.obolibrary.org/obo/dinto_DB01346 http://purl.obolibrary.org/obo/dinto_DB01353 http://purl.obolibrary.org/obo/dinto_DB01341 http://purl.obolibrary.org/obo/CHEBI_9073
prefixIRI	obo2:dinto_DB00158
prefLabel	folic acid
SMILES	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
Synonym	(2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid C19H19N7O6
xref	PDRhealth:http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/fol_0110.shtml ChEBI:27470 PharmGKB:PA449692 Wikipedia:http://en.wikipedia.org/wiki/Folic_Acid PubChem Compound:6037 PDB:FOL National Drug Code Directory:42291-533-10 Drugs.com:http://www.drugs.com/folic_acid.html PubChem Substance:46508092 ChemSpider:5815
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_27470	DRON	LOOM
http://purl.bioontology.org/ontology/VANDF/4017507	VANDF	LOOM
http://www.co-ode.org/ontologies/ont.owl#Folic_acid	DILON	LOOM
http://purl.bioontology.org/ontology/NDDF/001049	NDDF	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#5147	OCHV	LOOM
http://purl.bioontology.org/ontology/RCD/XM0lJ	RCD	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D005492	RH-MESH	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass01a62a3c_02dc_4d68_9fd8_7eb93af8397b	WWECA	LOOM
http://purl.bioontology.org/ontology/ATC/B03BB01	ATC	LOOM
http://localhost/plosthes.2017-1#4833	PLOSTHES	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039641	PDQ	LOOM
https://go.drugbank.com/drugs/DB00158	MDM	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Folic_Acid	APAONTO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017775	PMAPP-PMO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C510	NCIT	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	FOODON	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	CCONT	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	FB-CV	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	HHEAR	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	UPHENO	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	PECO	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	ONSTR	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	HINO	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	MAXO	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	ZP	LOOM
http://purl.obolibrary.org/obo/CHEBI_27470	OBA	LOOM
http://scai.fraunhofer.de/MSOntology#Folic_Acid	MSO	LOOM
http://purl.jp/bio/4/id/200906043183532720	IOBC	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassa1ab025b_f9b5_4834_8e9f_37ea35c90eff	WWECA	LOOM
http://doe-generated-ontology.com/OntoAD#C0016410	ONTOAD	LOOM
http://purl.bioontology.org/ontology/SNMI/F-BB390	SNMI	LOOM
http://purl.jp/bio/10/gmo/GMO_001033	GMO	LOOM
http://purl.obolibrary.org/obo/SCDO_0001329	SCDO	LOOM
http://purl.obolibrary.org/obo/XCO_0001113	XCO	LOOM
http://www.pepathway.org/peo/1.2#folic_acid	PE-O	LOOM
http://www.drugbank.ca/drugs/DB00158	FTC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.733.631.400	RH-MESH	LOOM
https://vodan-totafrica.info/ANC#Folicacid	VODAN_ANC	LOOM
http://purl.obolibrary.org/obo/MESH_D005492	BERO	LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0016410	MEDLINEPLUS	LOOM
http://www.co-ode.org/ontologies/galen#FolicAcid	GALEN	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000145892	NDFRT	LOOM
http://purl.bioontology.org/ontology/CPT/1011419	CPT	LOOM
http://purl.obolibrary.org/obo/NCIT_C510	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0006699	OMIT	LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_27470	NPO	LOOM
http://purl.bioontology.org/ontology/RXNORM/4511	RXNORM	LOOM
http://purl.bioontology.org/ontology/ATC/V04CX02	ATC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/63718003	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/MESH/D005492	MESH	LOOM