The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

levetiracetam
Synonyms

Keppra

levetiracetamum

Levetiracetam

C8H14N2O2

(-)-(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

(2S)-2-(2-oxopyrrolidin-1-yl)butanamide

UCB-L 059

(2R)-2-(2-oxopyrrolidin-1-yl)butanamide

(S)-(-)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

levetiracetam

ID

http://purl.obolibrary.org/obo/CHEBI_6437

activates

http://purl.obolibrary.org/obo/dinto_2212

AHFScode

28:12.92

ATCCode

N03AX14

binds

http://purl.obolibrary.org/obo/dinto_3628

http://purl.obolibrary.org/obo/dinto_2212

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_1440

CASRN

102767-28-2

DBBrand

keppra

DBname

levetiracetam

DBSynonym

levetiracetamum [inn-latin]

levitiracetam

levetiracetam [inn]

Definition

A pyrrolidinone and carboxamide that is N-methylpyrrolidin-2-one in which one of the methyl hydrogens is replaced by an aminocarbonyl group, while another is replaced by an ethyl group (the S enantiomer). An anticonvulsant, it is used for the treatment of epilepsy in both human and veterinary medicine.

has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000496

http://purl.obolibrary.org/obo/OAE_0000447

http://purl.obolibrary.org/obo/OAE_0000449

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000604

http://purl.obolibrary.org/obo/OAE_0000905

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000839

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0000335

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0000267

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0001167

http://purl.obolibrary.org/obo/OAE_0000411

http://purl.obolibrary.org/obo/OAE_0000443

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000412

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000482

http://purl.obolibrary.org/obo/OAE_0001370

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000883

http://purl.obolibrary.org/obo/OAE_0000103

http://purl.obolibrary.org/obo/OAE_0000340

http://purl.obolibrary.org/obo/OAE_0001026

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0001463

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0001433

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000386

http://purl.obolibrary.org/obo/OAE_0001275

http://purl.obolibrary.org/obo/OAE_0000455

http://purl.obolibrary.org/obo/OAE_0001105

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0000995

http://purl.obolibrary.org/obo/OAE_0001050

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000526

http://purl.obolibrary.org/obo/OAE_0001190

http://purl.obolibrary.org/obo/OAE_0000309

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000433

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000864

http://purl.obolibrary.org/obo/OAE_0000473

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0001164

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000344

http://purl.obolibrary.org/obo/OAE_0000495

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0001336

http://purl.obolibrary.org/obo/OAE_0000302

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000336

http://purl.obolibrary.org/obo/OAE_0001147

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000296

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000466

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0001366

http://purl.obolibrary.org/obo/OAE_0001458

http://purl.obolibrary.org/obo/OAE_0000246

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2212

http://purl.obolibrary.org/obo/dinto_3628

has role

http://purl.obolibrary.org/obo/CHEBI_35623

InChI

InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m1/s1

InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1

InChIKey

InChIKey=HPHUVLMMVZITSG-ZCFIWIBFSA-N

InChIKey=HPHUVLMMVZITSG-LURJTMIESA-N

inhibits

http://purl.obolibrary.org/obo/dinto_3628

is substrate of

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_1440

is transported by

http://purl.obolibrary.org/obo/dinto_0887

http://purl.obolibrary.org/obo/dinto_1440

label

levetiracetam

modulates

http://purl.obolibrary.org/obo/dinto_2212

prefixIRI

obo2:CHEBI_6437

prefLabel

levetiracetam

SMILES

CC[C@H](N1CCCC1=O)C(N)=O

CC[C@@H](N1CCCC1=O)C(N)=O

Synonym

Keppra

levetiracetamum

Levetiracetam

C8H14N2O2

(-)-(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

(2S)-2-(2-oxopyrrolidin-1-yl)butanamide

UCB-L 059

(2R)-2-(2-oxopyrrolidin-1-yl)butanamide

(S)-(-)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

levetiracetam

xref

Drugs.com:http://www.drugs.com/cdi/levetiracetam.html

CASRN:102767-28-2

Reaxys:8407472

National Drug Code Directory:0121-4802-05

KEGG COMPOUND:C07841

CiteXplore:22321334

DrugBank:DB01202

ChEMBL:352155

ChemSpider:390096

RxList:http://www.rxlist.com/cgi/generic3/keppra.htm

Wikipedia:http://en.wikipedia.org/wiki/Levetiracetam

Wikipedia:Levetiracetam

CiteXplore:22119754

PubChem Substance:46508406

KEGG DRUG:D00709

PubChem Compound:441341

PharmGKB:PA450206

Drugs Product Database (DPD):2247028

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/kep1561.shtml

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_6437 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6437 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6437 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6437 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6437 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6437 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6437 ECTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6437 EFO SAME_URI
http://purl.bioontology.org/ontology/NDFRT/N0000148644 NDFRT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000526173 PDQ LOOM
http://purl.obolibrary.org/obo/NCIT_C47581 BERO LOOM
https://go.drugbank.com/drugs/DB01202 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#31886 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP28566-5 LOINC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026566 PMAPP-PMO LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass961c0f62_7cdc_4fa3_868e_9435d1fe3e30 WWECA LOOM
http://purl.jp/bio/4/id/200906043074474621 IOBC LOOM
http://www.case.edu/EpSO.owl#Levetiracetam MEPO LOOM
http://purl.bioontology.org/ontology/ATC/N03AX14 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D000077287 MESH LOOM
http://www.case.edu/EpilepsyOntology.owl#Levetiracetam EPSO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387000003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4021198 VANDF LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass4bd070e8_58ba_4504_bbe6_ebad58f2d0ee WWECA LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6437 EFO LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Levetiracetam STMSO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47581 NCIT LOOM
http://purl.bioontology.org/ontology/NDDF/008058 NDDF LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass701f0dcd_c177_4dce_9351_a82092676c88 WWECA LOOM
http://stirdf.jst.go.jp/id/200907009255998673 IOBC LOOM
http://www.drugbank.ca/drugs/DB01202 FTC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0377265 OCHV LOOM
http://purl.bioontology.org/ontology/CPT/80177 CPT LOOM
http://www.co-ode.org/ontologies/galen#Levetiracetam GALEN LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060540 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/114477 RXNORM LOOM