The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

desipramine
Synonyms

desipramine

C18H22N2

3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine

monodemethylimipramine

Desipramin

Desipramine

3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE

desmethylimipramine

N-(3-methylaminopropyl)iminobibenzyl

(3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)(methyl)amine

DMI

5-(gamma-methylaminopropyl)iminodibenzyl

desipramina

norimipramine

desipraminum

demethylimipramine

ID

http://purl.obolibrary.org/obo/CHEBI_47781

AHFScode

28:16.04.28

altId

CHEBI:4448

CHEBI:47393

ATCCode

N06AA01

binds

http://purl.obolibrary.org/obo/dinto_2814

http://purl.obolibrary.org/obo/dinto_2652

http://purl.obolibrary.org/obo/dinto_1979

http://purl.obolibrary.org/obo/dinto_1972

http://purl.obolibrary.org/obo/dinto_1970

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_2496

http://purl.obolibrary.org/obo/dinto_0068

http://purl.obolibrary.org/obo/dinto_2789

http://purl.obolibrary.org/obo/dinto_0465

http://purl.obolibrary.org/obo/dinto_2907

http://purl.obolibrary.org/obo/dinto_3582

http://purl.obolibrary.org/obo/dinto_2646

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_3182

http://purl.obolibrary.org/obo/dinto_1005

http://purl.obolibrary.org/obo/dinto_0703

http://purl.obolibrary.org/obo/dinto_3887

http://purl.obolibrary.org/obo/dinto_1071

http://purl.obolibrary.org/obo/dinto_0234

http://purl.obolibrary.org/obo/dinto_2097

http://purl.obolibrary.org/obo/dinto_3504

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1959

blocks

http://purl.obolibrary.org/obo/dinto_3182

http://purl.obolibrary.org/obo/dinto_1005

http://purl.obolibrary.org/obo/dinto_0703

http://purl.obolibrary.org/obo/dinto_3887

http://purl.obolibrary.org/obo/dinto_1071

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_0234

http://purl.obolibrary.org/obo/dinto_2097

http://purl.obolibrary.org/obo/dinto_3504

CASRN

50-47-5

DBBrand

norpramin

pentofran

pertofran

pertrofane

sertofran

DBname

desipramine

DBSalt

desmethylimipramine hydrochloride

desipramine hydrochloride

DBSynonym

monodemethylimipramine

methylaminopropyliminodibenzyl

desipramin

desimpramine

desimipramine

desmethylimipramine

norpramine

norimipramine

dimethylimipramine

dezipramine

demethylimipramine

Definition

A dibenzoazepine that has formula C18H22N2.

has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000589

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0001431

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000660

http://purl.obolibrary.org/obo/OAE_0001069

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0001538

http://purl.obolibrary.org/obo/OAE_0000608

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0000632

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0000995

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0001068

http://purl.obolibrary.org/obo/OAE_0000268

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0001742

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0001336

http://purl.obolibrary.org/obo/OAE_0000491

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000487

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0001291

http://purl.obolibrary.org/obo/OAE_0001001

http://purl.obolibrary.org/obo/OAE_0000881

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000500

http://purl.obolibrary.org/obo/OAE_0000534

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_0068

has role

http://purl.obolibrary.org/obo/CHEBI_37955

http://purl.obolibrary.org/obo/CHEBI_48873

http://purl.obolibrary.org/obo/CHEBI_50949

http://purl.obolibrary.org/obo/CHEBI_23924

http://purl.obolibrary.org/obo/CHEBI_37890

http://purl.obolibrary.org/obo/CHEBI_35640

InChI

InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3

InChIKey

InChIKey=HCYAFALTSJYZDH-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2814

http://purl.obolibrary.org/obo/dinto_2652

http://purl.obolibrary.org/obo/dinto_1979

http://purl.obolibrary.org/obo/dinto_1972

http://purl.obolibrary.org/obo/dinto_1970

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_2496

http://purl.obolibrary.org/obo/dinto_0068

http://purl.obolibrary.org/obo/dinto_2789

http://purl.obolibrary.org/obo/dinto_0465

is metabolised by

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_1959

is substrate of

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_1959

label

desipramine

may interact with

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_102524

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_2549

http://purl.obolibrary.org/obo/CHEBI_41774

http://purl.obolibrary.org/obo/CHEBI_28918

http://purl.obolibrary.org/obo/CHEBI_66876

http://purl.obolibrary.org/obo/CHEBI_8093

http://purl.obolibrary.org/obo/CHEBI_37924

http://purl.obolibrary.org/obo/CHEBI_4670

http://purl.obolibrary.org/obo/dinto_DB00723

http://purl.obolibrary.org/obo/dinto_DB00476

http://purl.obolibrary.org/obo/CHEBI_42944

http://purl.obolibrary.org/obo/dinto_DB00209

http://purl.obolibrary.org/obo/dinto_DB01364

http://purl.obolibrary.org/obo/dinto_DB01064

http://purl.obolibrary.org/obo/dinto_DB00857

http://purl.obolibrary.org/obo/CHEBI_8874

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/CHEBI_149226

http://purl.obolibrary.org/obo/CHEBI_53289

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/dinto_DB01291

http://purl.obolibrary.org/obo/CHEBI_3699

http://purl.obolibrary.org/obo/CHEBI_51364

http://purl.obolibrary.org/obo/dinto_DB01366

http://purl.obolibrary.org/obo/CHEBI_6794

http://purl.obolibrary.org/obo/CHEBI_18243

http://purl.obolibrary.org/obo/dinto_DB00780

http://purl.obolibrary.org/obo/CHEBI_9449

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/dinto_DB00237

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/dinto_DB00365

http://purl.obolibrary.org/obo/CHEBI_10119

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/CHEBI_3387

http://purl.obolibrary.org/obo/CHEBI_9635

http://purl.obolibrary.org/obo/CHEBI_51209

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/dinto_DB01363

http://purl.obolibrary.org/obo/dinto_DB00397

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/dinto_DB01247

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/CHEBI_63628

http://purl.obolibrary.org/obo/CHEBI_45716

http://purl.obolibrary.org/obo/dinto_DB00382

http://purl.obolibrary.org/obo/dinto_DB01171

http://purl.obolibrary.org/obo/CHEBI_5557

http://purl.obolibrary.org/obo/dinto_DB01365

http://purl.obolibrary.org/obo/dinto_DB01105

http://purl.obolibrary.org/obo/CHEBI_28593

http://purl.obolibrary.org/obo/CHEBI_70707

http://purl.obolibrary.org/obo/dinto_DB00488

http://purl.obolibrary.org/obo/CHEBI_63620

http://purl.obolibrary.org/obo/dinto_DB00503

http://purl.obolibrary.org/obo/CHEBI_18357

http://purl.obolibrary.org/obo/CHEBI_10124

http://purl.obolibrary.org/obo/CHEBI_46631

http://purl.obolibrary.org/obo/CHEBI_68575

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/CHEBI_195280

http://purl.obolibrary.org/obo/dinto_DB00816

http://purl.obolibrary.org/obo/dinto_DB01208

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/dinto_DB01623

http://purl.obolibrary.org/obo/CHEBI_65349

http://purl.obolibrary.org/obo/CHEBI_5118

http://purl.obolibrary.org/obo/dinto_DB06700

modulates

http://purl.obolibrary.org/obo/dinto_3182

http://purl.obolibrary.org/obo/dinto_1005

http://purl.obolibrary.org/obo/dinto_0703

http://purl.obolibrary.org/obo/dinto_3887

http://purl.obolibrary.org/obo/dinto_1071

http://purl.obolibrary.org/obo/dinto_0392

http://purl.obolibrary.org/obo/dinto_0234

http://purl.obolibrary.org/obo/dinto_2097

http://purl.obolibrary.org/obo/dinto_3504

prefixIRI

obo2:CHEBI_47781

prefLabel

desipramine

related with

http://purl.obolibrary.org/obo/dinto_2907

http://purl.obolibrary.org/obo/dinto_3582

http://purl.obolibrary.org/obo/dinto_2646

SMILES

CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12

CNCCCN1c2ccccc2CCc2ccccc12

Synonym

desipramine

C18H22N2

3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine

monodemethylimipramine

Desipramin

Desipramine

3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE

desmethylimipramine

N-(3-methylaminopropyl)iminobibenzyl

(3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)(methyl)amine

DMI

5-(gamma-methylaminopropyl)iminodibenzyl

desipramina

norimipramine

desipraminum

demethylimipramine

xref

PDB:DSM

BindingDB:35229

National Drug Code Directory:0781-1971-01

Drugs.com:http://www.drugs.com/cdi/desipramine.html

ChemSpider:2888

ChEBI:47781

PharmGKB:PA449233

Wikipedia:http://en.wikipedia.org/wiki/Desipramine

PDBeChem:DSM

Drugs Product Database (DPD):2216272

KEGG DRUG:D07791

KEGG COMPOUND:C06943

RxList:http://www.rxlist.com/cgi/generic2/desipram.htm

DrugBank:DB01151

ChEMBL:106243

PubChem Compound:2995

CASRN:50-47-5

CASRN:1432747

NIST Chemistry WebBook:50-47-5

Guide To Pharmacology:2399

IUPHAR:2399

PubChem Substance:46504624

Wikipedia:Desipramine

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_47781 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 ECTO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 HINO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_47781 ODNAE SAME_URI
http://purl.bioontology.org/ontology/CSP/0314-7106 CRISP LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 CHEBI LOOM
http://purl.obolibrary.org/obo/MESH_D003891 BERO LOOM
http://purl.bioontology.org/ontology/SNMI/C-62270 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.240.281 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Desipramine GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3809 OCHV LOOM
http://purl.bioontology.org/ontology/RCD/x01Ay RCD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0011685 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004929 LOINC LOOM
http://stirdf.jst.go.jp/id/200907055696767008 IOBC LOOM
https://go.drugbank.com/drugs/DB01151 MDM LOOM
http://purl.bioontology.org/ontology/VANDF/4019708 VANDF LOOM
http://purl.bioontology.org/ontology/NDDF/004602 NDDF LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassb32ae96b_9337_441f_a45b_8e7efc039775 WWECA LOOM
http://www.case.edu/EpSO.owl#Desipramine MEPO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017965 PMAPP-PMO LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Desipramine STMSO LOOM
http://purl.bioontology.org/ontology/RXNORM/3247 RXNORM LOOM
http://purl.jp/bio/4/id/200906005384567140 IOBC LOOM
http://purl.bioontology.org/ontology/ATC/N06AA01 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147800 NDFRT LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147800 ODAE LOOM
http://www.case.edu/EpilepsyOntology.owl#Desipramine EPSO LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Desipramine APAONTO LOOM
http://purl.bioontology.org/ontology/MESH/D003891 MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372705002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/LP16103-1 LOINC LOOM
http://purl.obolibrary.org/obo/OMIT_0005167 OMIT LOOM
http://neuromorpho.org/ontologies/experimentconditionH.owl#NMOOt_1191 NMOBR LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_47781 ODNAE LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003891 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB01151 FTC LOOM
http://purl.obolibrary.org/obo/NCIT_C61700 BERO LOOM
http://purl.bioontology.org/ontology/CSP/0314-7106 CRISP LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61700 NCIT LOOM