The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	ziprasidone
Synonyms	ziprasidone ziprasidonum 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one ziprasidona C21H21ClN4OS Ziprasidone
ID	http://purl.obolibrary.org/obo/CHEBI_10119
ATCCode	N05AE04
binds	http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_3340 http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_3203 http://purl.obolibrary.org/obo/dinto_4010 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_2858 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0656 http://purl.obolibrary.org/obo/dinto_1005 http://purl.obolibrary.org/obo/dinto_0703 http://purl.obolibrary.org/obo/dinto_3887 http://purl.obolibrary.org/obo/dinto_0909 http://purl.obolibrary.org/obo/dinto_0166 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_2705 http://purl.obolibrary.org/obo/dinto_1166 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_2097 http://purl.obolibrary.org/obo/dinto_3332 http://purl.obolibrary.org/obo/dinto_1123 http://purl.obolibrary.org/obo/dinto_1135 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_1956
blocks	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_3340 http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_3203 http://purl.obolibrary.org/obo/dinto_4010 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_2858 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0656 http://purl.obolibrary.org/obo/dinto_1005 http://purl.obolibrary.org/obo/dinto_0703 http://purl.obolibrary.org/obo/dinto_3887 http://purl.obolibrary.org/obo/dinto_0909 http://purl.obolibrary.org/obo/dinto_0166 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_2705 http://purl.obolibrary.org/obo/dinto_1166 http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_2097 http://purl.obolibrary.org/obo/dinto_3332 http://purl.obolibrary.org/obo/dinto_1123 http://purl.obolibrary.org/obo/dinto_1135
CASRN	146939-27-7
DBBrand	geodon zeldox geodon oral
DBname	ziprasidone
DBSynonym	ziprasidone mesylate trihydrate ziprasidone hydrochloride
Definition	A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0001297 http://purl.obolibrary.org/obo/OAE_0001059 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001046 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0001360 http://purl.obolibrary.org/obo/OAE_0001369 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0001013 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000935 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000426 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000612 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0001063 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000386 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0001003 http://purl.obolibrary.org/obo/OAE_0001050 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0001153 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000433 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001152 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000421 http://purl.obolibrary.org/obo/OAE_0000592 http://purl.obolibrary.org/obo/OAE_0000516 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0000716 http://purl.obolibrary.org/obo/OAE_0001170 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0001497 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0001458 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0392
has role	http://purl.obolibrary.org/obo/CHEBI_37956 http://purl.obolibrary.org/obo/CHEBI_35471 http://purl.obolibrary.org/obo/CHEBI_48876 http://purl.obolibrary.org/obo/CHEBI_48561 http://purl.obolibrary.org/obo/CHEBI_48279 http://purl.obolibrary.org/obo/CHEBI_35476
InChI	InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
InChIKey	InChIKey=MVWVFYHBGMAFLY-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0901
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956
is substrate of	http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2990 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_1956
label	ziprasidone
may interact with	http://purl.obolibrary.org/obo/CHEBI_8212 http://purl.obolibrary.org/obo/CHEBI_71219 http://purl.obolibrary.org/obo/dinto_DB00556 http://purl.obolibrary.org/obo/dinto_DB05271 http://purl.obolibrary.org/obo/CHEBI_36791 http://purl.obolibrary.org/obo/CHEBI_5280 http://purl.obolibrary.org/obo/CHEBI_337298 http://purl.obolibrary.org/obo/dinto_DB01142 http://purl.obolibrary.org/obo/CHEBI_6838 http://purl.obolibrary.org/obo/CHEBI_8021 http://purl.obolibrary.org/obo/CHEBI_127780 http://purl.obolibrary.org/obo/dinto_DB00243 http://purl.obolibrary.org/obo/CHEBI_3647 http://purl.obolibrary.org/obo/CHEBI_8707 http://purl.obolibrary.org/obo/dinto_DB00196 http://purl.obolibrary.org/obo/CHEBI_2955 http://purl.obolibrary.org/obo/dinto_DB00344 http://purl.obolibrary.org/obo/dinto_DB00757 http://purl.obolibrary.org/obo/CHEBI_156095 http://purl.obolibrary.org/obo/CHEBI_42944 http://purl.obolibrary.org/obo/dinto_DB00540 http://purl.obolibrary.org/obo/CHEBI_63611 http://purl.obolibrary.org/obo/CHEBI_71253 http://purl.obolibrary.org/obo/CHEBI_8871 http://purl.obolibrary.org/obo/CHEBI_47499 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/CHEBI_31515 http://purl.obolibrary.org/obo/dinto_DB00726 http://purl.obolibrary.org/obo/CHEBI_5613 http://purl.obolibrary.org/obo/dinto_DB04855 http://purl.obolibrary.org/obo/CHEBI_8356 http://purl.obolibrary.org/obo/dinto_DB00104 http://purl.obolibrary.org/obo/CHEBI_63609 http://purl.obolibrary.org/obo/CHEBI_47780 http://purl.obolibrary.org/obo/CHEBI_63622 http://purl.obolibrary.org/obo/CHEBI_48538 http://purl.obolibrary.org/obo/CHEBI_15765 http://purl.obolibrary.org/obo/CHEBI_53289 http://purl.obolibrary.org/obo/CHEBI_49603 http://purl.obolibrary.org/obo/CHEBI_6780 http://purl.obolibrary.org/obo/CHEBI_45081 http://purl.obolibrary.org/obo/CHEBI_9566 http://purl.obolibrary.org/obo/CHEBI_3181 http://purl.obolibrary.org/obo/CHEBI_51364 http://purl.obolibrary.org/obo/CHEBI_4717 http://purl.obolibrary.org/obo/CHEBI_5893 http://purl.obolibrary.org/obo/dinto_DB00270 http://purl.obolibrary.org/obo/CHEBI_63598 http://purl.obolibrary.org/obo/CHEBI_75984 http://purl.obolibrary.org/obo/CHEBI_5121 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00308 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_2618 http://purl.obolibrary.org/obo/CHEBI_8888 http://purl.obolibrary.org/obo/CHEBI_52172 http://purl.obolibrary.org/obo/CHEBI_100246 http://purl.obolibrary.org/obo/CHEBI_30621 http://purl.obolibrary.org/obo/CHEBI_3387 http://purl.obolibrary.org/obo/CHEBI_49375 http://purl.obolibrary.org/obo/CHEBI_9635 http://purl.obolibrary.org/obo/CHEBI_8466 http://purl.obolibrary.org/obo/CHEBI_3720 http://purl.obolibrary.org/obo/CHEBI_3723 http://purl.obolibrary.org/obo/CHEBI_50841 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/CHEBI_6807 http://purl.obolibrary.org/obo/CHEBI_9467 http://purl.obolibrary.org/obo/CHEBI_65173 http://purl.obolibrary.org/obo/CHEBI_45716 http://purl.obolibrary.org/obo/dinto_DB00382 http://purl.obolibrary.org/obo/CHEBI_28593 http://purl.obolibrary.org/obo/dinto_DB01118 http://purl.obolibrary.org/obo/dinto_DB00199 http://purl.obolibrary.org/obo/CHEBI_4657 http://purl.obolibrary.org/obo/CHEBI_15854 http://purl.obolibrary.org/obo/dinto_DB01218 http://purl.obolibrary.org/obo/dinto_DB01026 http://purl.obolibrary.org/obo/CHEBI_8427 http://purl.obolibrary.org/obo/CHEBI_8428 http://purl.obolibrary.org/obo/CHEBI_71226 http://purl.obolibrary.org/obo/CHEBI_47781 http://purl.obolibrary.org/obo/CHEBI_195280 http://purl.obolibrary.org/obo/dinto_DB01208 http://purl.obolibrary.org/obo/CHEBI_38940 http://purl.obolibrary.org/obo/dinto_DB00934 http://purl.obolibrary.org/obo/dinto_DB01623 http://purl.obolibrary.org/obo/CHEBI_4681 http://purl.obolibrary.org/obo/CHEBI_2675 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/CHEBI_2666 http://purl.obolibrary.org/obo/CHEBI_5118
modulates	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3182 http://purl.obolibrary.org/obo/dinto_3340 http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_3203 http://purl.obolibrary.org/obo/dinto_4010 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_2858 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0656 http://purl.obolibrary.org/obo/dinto_1005 http://purl.obolibrary.org/obo/dinto_0703 http://purl.obolibrary.org/obo/dinto_3887 http://purl.obolibrary.org/obo/dinto_0909 http://purl.obolibrary.org/obo/dinto_0166 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_2705 http://purl.obolibrary.org/obo/dinto_1166 http://purl.obolibrary.org/obo/dinto_0392 http://purl.obolibrary.org/obo/dinto_0234 http://purl.obolibrary.org/obo/dinto_2097 http://purl.obolibrary.org/obo/dinto_3332 http://purl.obolibrary.org/obo/dinto_1123 http://purl.obolibrary.org/obo/dinto_1135
prefixIRI	obo2:CHEBI_10119
prefLabel	ziprasidone
SMILES	ClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12
Synonym	ziprasidone ziprasidonum 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one ziprasidona C21H21ClN4OS Ziprasidone
xref	Patent:EP281309 ChemSpider:54841 Drugs.com:http://www.drugs.com/cdi/ziprasidone.html RxList:http://www.rxlist.com/cgi/generic2/ziprasidone.htm National Drug Code Directory:0049-3960-60 Wikipedia:http://en.wikipedia.org/wiki/Ziprasidone Beilstein:6669199 PubChem Compound:60854 Patent:US4831031 DrugBank:146939-27-7 IUPHAR:59 ChEMBL:133664 CASRN:146939-27-7 Wikipedia:Ziprasidone KEGG DRUG:D08687 KEGG COMPOUND:C07568 ChEBI:10119 DrugBank:DB00246 PharmGKB:PA451974 PubChem Substance:46507627 Guide To Pharmacology:59
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_10119	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	GO-PLUS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	ECTO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	ODNAE	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10119	OBA	LOOM
http://www.case.edu/EpilepsyOntology.owl#Ziprasidone	EPSO	LOOM
http://www.case.edu/EpSO.owl#Ziprasidone	MEPO	LOOM
http://purl.bioontology.org/ontology/ATC/N05AE04	ATC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148690	NDFRT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47788	NCIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C47788	BERO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0380393	OCHV	LOOM
http://www.drugbank.ca/drugs/DB00246	FTC	LOOM
http://purl.bioontology.org/ontology/RXNORM/115698	RXNORM	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148690	ODAE	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C092292	RH-MESH	LOOM
https://go.drugbank.com/drugs/DB00246	MDM	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026527	PMAPP-PMO	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass19a14603_04a5_4ad8_94c7_2ba70ed4dbe6	WWECA	LOOM
http://purl.bioontology.org/ontology/VANDF/4021249	VANDF	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	ECTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10119	ODNAE	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU015780	LOINC	LOOM
http://purl.bioontology.org/ontology/MESH/C092292	MESH	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/409356003	SNOMEDCT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#31919	OCHV	LOOM
http://purl.bioontology.org/ontology/LNC/LP31713-8	LOINC	LOOM