loading...| Preferred Name | kernicterus | |
| Synonyms |
bilirubin encephalopathy |
|
| Definitions |
brain disorder associated with high levels of bilrubin; clinical features include athetosis, muscle spasticity or hypotonia, impaired vertical gaze, and deafness; nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the blood-brain barrier; this condition occurs primarily in neonates with perinatal blood incompatibilities, but may rarely occur in adults. |
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| ID |
http://purl.bioontology.org/ontology/CSP/1653-7303 |
|
| altLabel |
bilirubin encephalopathy |
|
| cui |
C0022610 |
|
| definition |
brain disorder associated with high levels of bilrubin; clinical features include athetosis, muscle spasticity or hypotonia, impaired vertical gaze, and deafness; nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the blood-brain barrier; this condition occurs primarily in neonates with perinatal blood incompatibilities, but may rarely occur in adults. |
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| DID |
1653-7303 |
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| Inverse of RB | ||
| Inverse of RO | ||
| notation |
1653-7303 |
|
| prefLabel |
kernicterus |
|
| tui |
T047 |
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| subClassOf |