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Chemical Entities of Biological Interest Ontology
Last uploaded:
December 1, 2024
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| Preferred Name | insulin | |
| Synonyms |
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| Definitions |
A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_145810 |
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| database_cross_reference |
PMID:12137720 PMID:6069707 PMID:25848166 PMID:19251032 Wikipedia:Insulin PMID:5941964
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| definition |
A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies.
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| has_obo_namespace |
chebi_ontology
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| id |
CHEBI:145810
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| in_subset | ||
| label |
insulin
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| notation |
CHEBI:145810
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| prefLabel |
insulin
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| treeView |
http://purl.obolibrary.org/obo/CHEBI_24533 |
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| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_24533 |
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