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Cell Culture Ontology
| Preferred Name | primary angle closure glaucoma | |
| Synonyms |
primary angle closure glaucoma primary angle-closure glaucoma |
|
| Definitions |
A type of glaucoma with optic nerve damage in an eye that has evidence of angle closure and in which there is no evidence of a secondary cause. Evidence of optic nerve damage can include s optic disc abnormalities (Vertical cup:disc ratio over the 97. 5th percentile in the normal population), visual field defects. The role of increased intraocular pressure (IOP) in glaucoma is debated, but an IOP exceeding the 99. 5th percentile of the normal population may be considered to support the diagnosis. An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_1001506 |
|
| curated_content_resource |
https://search.clinicalgenome.org/kb/conditions/MONDO:0001868 |
|
| database_cross_reference |
NCIT:C34640 UMLS:C0017606 MONDO:0001868 ICD10CM:H40.2 MedDRA:10002500 ICD9:365.20 SCTID:392288006 MEDGEN:42225 NCIt:C34640 DOID:1405 HP:0012109 ICD9:365.2
|
|
| definition |
A type of glaucoma with optic nerve damage in an eye that has evidence of angle closure and in which there is no evidence of a secondary cause. Evidence of optic nerve damage can include s optic disc abnormalities (Vertical cup:disc ratio over the 97. 5th percentile in the normal population), visual field defects. The role of increased intraocular pressure (IOP) in glaucoma is debated, but an IOP exceeding the 99. 5th percentile of the normal population may be considered to support the diagnosis. An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.
|
|
| gwas_trait |
true
|
|
| has_exact_synonym |
primary angle closure glaucoma primary angle-closure glaucoma
|
|
| IAO_0000233 | ||
| IAO_0006012 |
2024-12-01
|
|
| id |
EFO:1001506
|
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#clingen http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#obsoletion_candidate |
|
| label |
primary angle closure glaucoma
|
|
| notation |
EFO:1001506
|
|
| preferred label |
primary angle closure glaucoma
|
|
| prefLabel |
primary angle closure glaucoma
|
|
| skos_exactMatch |
http://linkedlifedata.com/resource/umls/id/C0017606 http://purl.obolibrary.org/obo/EFO_1001506 http://purl.obolibrary.org/obo/DOID_1405 http://identifiers.org/snomedct/392288006 |
|
| term editor |
Dani Welter
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |