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Cell Culture Ontology
| Preferred Name | HELLP syndrome | |
| Synonyms |
hypertension, pregnancy-induced hemolysis, elevated liver enzymes, lowered platelets toxaemia of pregnancy hemolysis, elevated liver enzymes, and low platelet count toxemia of pregnancy PREECLAMPSIA/eclampsia 1 PEE1 PREG1 HELLP syndrome (disorder) hemolysis-elevated liver enzymes-low platelet count syndrome hemolysis, elevated liver enzymes, low platelets in pregnancy syndrome of haemolysis, elevated liver enzymes and low platelet HELLP syndrome hemolysis-elevated liver enzymes-low platelets syndrome HELLP Syndrome |
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| Definitions |
A life-threatening condition that can potentially complicate pregnancy. It is named for 3 features of the condition: H emolysis, E levated L iver enzyme levels, and L ow P latelet levels. It typically occurs in the last 3 months of pregnancy (the third trimester) but can also start soon after delivery. A wide range of non-specific symptoms may be present in women with HELLP syndrome. Symptoms may include fatigue; malaise; fluid retention and excess weight gain; headache; nausea and vomiting; pain in the upper right or middle of the abdomen; blurry vision; and rarely, nosebleed or seizures. The cause of HELLP syndrome is not known, but certain risk factors have been associated with the condition. It is most common in women with preeclampsia or eclampsia. If not diagnosed and treated quickly, HELLP syndrome can lead to serious complications for the mother and baby.The main treatment is to deliver the baby as soon as possible, even if premature. Treatment may also include medications needed for the mother or baby, and blood transfusion for severe bleeding problems. A severe pre-eclampsia characterized by hemolysis, elevated liver enzyme and low platelet count. |
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| ID |
http://www.ebi.ac.uk/efo/EFO_0007297 |
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| database_cross_reference |
Orphanet:244242 UMLS:C0162739 MeSH:D017359 MedDRA:10049058 MESH:D017359 MEDGEN:58162 icd11.foundation:1748922908 MONDO:0008585 NCIT:C84750 DOID:13133 GARD:8528
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| definition |
A life-threatening condition that can potentially complicate pregnancy. It is named for 3 features of the condition: H emolysis, E levated L iver enzyme levels, and L ow P latelet levels. It typically occurs in the last 3 months of pregnancy (the third trimester) but can also start soon after delivery. A wide range of non-specific symptoms may be present in women with HELLP syndrome. Symptoms may include fatigue; malaise; fluid retention and excess weight gain; headache; nausea and vomiting; pain in the upper right or middle of the abdomen; blurry vision; and rarely, nosebleed or seizures. The cause of HELLP syndrome is not known, but certain risk factors have been associated with the condition. It is most common in women with preeclampsia or eclampsia. If not diagnosed and treated quickly, HELLP syndrome can lead to serious complications for the mother and baby.The main treatment is to deliver the baby as soon as possible, even if premature. Treatment may also include medications needed for the mother or baby, and blood transfusion for severe bleeding problems. A severe pre-eclampsia characterized by hemolysis, elevated liver enzyme and low platelet count.
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| has_exact_synonym |
HELLP syndrome (disorder) hemolysis-elevated liver enzymes-low platelet count syndrome hemolysis, elevated liver enzymes, low platelets in pregnancy syndrome of haemolysis, elevated liver enzymes and low platelet HELLP syndrome hemolysis-elevated liver enzymes-low platelets syndrome HELLP Syndrome
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| has_related_synonym |
hypertension, pregnancy-induced hemolysis, elevated liver enzymes, lowered platelets toxaemia of pregnancy hemolysis, elevated liver enzymes, and low platelet count toxemia of pregnancy PREECLAMPSIA/eclampsia 1 PEE1 PREG1
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| id |
EFO:0007297
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disorder |
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| label |
HELLP syndrome
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| notation |
EFO:0007297
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| preferred label |
HELLP syndrome
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| prefLabel |
HELLP syndrome
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| see also |
https://rarediseases.info.nih.gov/diseases/8528/hellp-syndrome |
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| skos_closeMatch | ||
| skos_exactMatch |
http://identifiers.org/mesh/D017359 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/1748922908 http://purl.obolibrary.org/obo/Orphanet_244242 http://purl.obolibrary.org/obo/NCIT_C84750 http://purl.obolibrary.org/obo/DOID_13133 http://identifiers.org/medgen/58162 |
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| term editor |
Sirarat Sarntivijai
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| subClassOf |
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